Diagnostic Testing for Pulmonary Vascular Disease. Non-invasive Testing

[Cyanosis for more than 4 years in a girl aged 4 years and 3 months]

Mao-Lan Wu, Xiang-Rong Zheng, Yan-Tong Zhu, Guo-Yuan Zhang, Chen-Tao Liu, Xia Wang, Yong-Jun TangXiangya Hospital and Central South University.China Chinese Journal of Contemporary PediatricsZhongguo Dang Dai Er Ke Za Zhi 2020; 22: 387-390DOI: 10.7499/j.issn.1008-8830.1910147 AbstractA girl, aged 4 years and 3 months, presented with cyanosis of the lips shortly after birth. She then experienced shortness of […]

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Incidental diagnosis of four pulmonary arteriovenous fistulas during patent foramen ovale closure: a case report

Alessandro Andreis, Gabriella Agnoletti, Paolo ScacciatellaCittà della Salute e della Scienza di Torino Hospital and University of Turin.Italy Cardiology in the YoungCardiol Young 2020; 30: 1363-1365DOI: 10.1017/S1047951120002152 Abstractryptogenic cerebral ischemia in young patients is commonly ascribed to paradoxical embolism. We report the clinical case of a young patient with cryptogenic stroke and a patent foramen ovale,

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Risk factors for severe pertussis in children and the application of exchange transfusion

Qihong Chen, Lihua Lin, Shuping Xiong, DandanGe, Yungang YangFirst Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University. Pediatric Key Laboratory of Xiamen. Pediatric Quality Control Center of Xiamen. China Pediatric ResearchPediatr Res 2025; DOI: 10.1038/s41390-025-04118-6 AbstractObjective: To identify risk factors for severe pertussis and assess the efficacy of exchange transfusion in children.Methods: We analyzed pediatric pertussis

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Genotype-Phenotype Correlations in Children with HHT

Alexandra Kilian, Giuseppe A. Latino, Andrew J. White, Dewi Clark, Murali M. Chakinala, Felix Ratjen, Jamie McDonald, Kevin J. Whitehead, James R. Gossage, Doris Lin, Katharine Henderson, Jeffrey Pollak, Justin P. McWilliams, Helen Kim, Michael T. Lawton, Marie E. Faughnan, the Brain Vascular Malformation Consortium HHT Investigator GroupSt. Michael’s Hospital and Li Ka Shing Knowledge

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Safety and Feasibility of Early Targeted Neonatal Echocardiography and a Focused Assessment Protocol in Neonates With Congenital Diaphragmatic Hernia

John T. Wren Jr., Rachael M. Hyland, Stephanie Acosta, Patrick J. McNamaraUniversity of Iowa Healthcare.United States EchocardiographyEchocardiography 2025; DOI: 10.1111/echo.70189 AbstractObjective: Congenital diaphragmatic hernia (CDH) is a complex disease with significant morbidity and mortality. The use of echocardiography, traditionally a pediatric cardiology echocardiogram (PCE), has significantly advanced the management of CDH but its availability can be limited,

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Role of phosphodiesterase-3 inhibitor in cardiorespiratory fitness and functional class of patients with pulmonary hypertension: A randomized, double-blind, placebo-controlled trial

Sefri N. Sofia, Udin Bahrudin, Ilham Uddin, Muhammad A. Sobirin, Erna Setiawati, Galuh Hardaningsih, Kevin C. Tjandra, Edward K. S. LimijadiUniversitas Diponegoro. Dr. Kariadi Hospital. Indonesia Narra JNarra J 2025; 5: DOI: 10.52225/narra.v5i1.1301 AbstractMany patients with acyanotic shunt congenital heart disease (CHD) are diagnosed only in adulthood, by which time pulmonary hypertension (PH) has developed, impairing

Role of phosphodiesterase-3 inhibitor in cardiorespiratory fitness and functional class of patients with pulmonary hypertension: A randomized, double-blind, placebo-controlled trial Read More »

Bronchopulmonary Dysplasia-Associated Pulmonary Hypertension: Screening and Management

Samuel F. Schaeffer, Bwaar Omer, Akshaya Vachhaarajani, Chaitanya PanchangamUniversity of Missouri.United States NeoreviewsNeoreviews 2025; 26: e316-e327DOI: 10.1542/neo.26-5-013 AbstractScreening for pulmonary hypertension (PH) in infants with bronchopulmonary dysplasia (BPD) was recommended by the American Thoracic Society in 2015. However, the definition of BPD has since changed. This review summarizes the current definition of BPD, the recommendations and

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Factors Associated with Early-Childhood Ipsilateral Perfusion Abnormalities among Patients with Congenital Diaphragmatic Hernia

Akila B. Ramaraj, Hannah V. Breitschopf, Kylie I. Holden, Vikas S. Gupta, Carrie L. Foster, Ashley H. Ebanks, Chase M. Miller, Terry L. Buchmiller, Matthew T. Harting, Rebecca A. Stark, CDH Study GroupSeattle Children’s Hospital and UConn Health. McGovern Medical School at the University of Texas Health Science Center and Children’s Memorial Hermann Hospital. Boston

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Congenital atresia of unilateral pulmonary veins associated with a single ventricle: a rare case report and literature review

Hsing-Yuan Lee, Betau Hwang, Pi-Chang Lee, Sheng-Ling Jan, C.C. Laura MengTaoyuan Armed Force General Hospital.Taiwan Circulation JournalCirc J 2008; 72: 1544-1546DOI: 10.1253/circj.cj-07-0516 AbstractCongenital atresia or extreme hypoplasia of individual pulmonary veins is a rare condition that is usually asymptomatic if it only involves 1 or 2 segments of the lungs. It may be fatal if it

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Right Ventricular Stiffening and Function Are Associated With Main Pulmonary Artery Remodeling in a Rat Model of Pulmonary Hypertension

Bahram Mirani, John D. Dauz, Kana Yazaki, Neda Latifi, J. Paul Santerre, Michelle P. Bendeck, Craig A. Simmons, Mark K. FriedbergUniversity of Toronto, Ted Rogers Centre for Heart Research and Hospital for Sick Children. Beth Israel Deaconess Medical Center and Harvard Medical School. University of South Florida.Canada and United States Arteriosclerosis, Thrombosis and Vascular BiologyArterioscler,

Right Ventricular Stiffening and Function Are Associated With Main Pulmonary Artery Remodeling in a Rat Model of Pulmonary Hypertension Read More »

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