Diagnostic Testing for Pulmonary Vascular Disease. Non-invasive Testing

Screening Echocardiography Identifies Risk Factors for Pulmonary Hypertension at Discharge in Premature Infants with Bronchopulmonary Dysplasia

B. A. Madden, M. R. Conaway, S. A. Zanelli, M. A. McCullochAnn and Robert H. Lurie Children’s Hospital of Chicago. University of Virginia and University of Virginia Children’s Hospital.United States Pediatric CardiologyPediatr Cardiol 2022; 43: 1743-1751DOI: 10.1007/s00246-022-02911-2 AbstractHypothesis: Premature infants with bronchopulmonary dysplasia (BPD) are at increased risk of secondary pulmonary hypertension (BPD-PH). Prior studies yielded mixed […]

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Oxygen Saturation Index in Neonates with a Congenital Diaphragmatic Hernia: A Retrospective Cohort Study

Emily J. J. Horn-Oudshoorn, Marijn J. Vermeulen, Kelly J. Crossley, Suzan C. M. Cochius-den Otter, J. Marco Schnater, Irwin K.M. Reiss, Philip L. J. DeKoninckErasmus MC University Medical Center, Rotterdam. Monash University. Netherlands and Australia NeonatologyNeonatology 2022; 119: 111-118DOI: 10.1159/000520883 AbstractIntroduction: The oxygenation index (OI) is a marker for respiratory disease severity and adverse neonatal outcomes. The

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Pulmonary hypertension screening in children with sickle cell disease

Kok Hoe Chan, Syeda Hiba Rizvi, Wilfredo De Jesus-Rojas, James M. Stark, Ricardo A. Mosquera, Adriana Carolina Prada-Ruiz, Traci Gonzales, Deborah L. Brown, Neethu M. Menon, Trinh T. Nguyen, Cindy K. Jon, Aravind YadavMcGovern Medical School at the University of Texas Health Science Center at Houston. Ponce Health Science University and Ponce Research Institute. Baylor

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The association between pulmonary vascular disease and respiratory improvement in infants with type I severe bronchopulmonary dysplasia

Ryan J. Carpenter, Nina Srdanovic, Karen Rychlik, Shawn K. Sen, Nicholas F. M. Porta, Aaron E. Hamvas, Karna Murthy, Amanda L. HauckLurie Children’s Hospital of Chicago and Northwestern University.United States Journal of PerinatologyJ Perinatol 2022; 42: 788-795DOI: 10.1038/s41372-022-01386-6 AbstractObjective: To describe the association between echocardiographic measures of pulmonary vascular disease and time to respiratory improvement among infants

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High altitude simulation testing in patients with congenital diaphragmatic hernia

Ashlyn E. Whitlock, Catherine A. Sheils, Jill M. Zalieckas, Gary Visner, Mary Mullen, Mollie Studley, Lindsay Lemire, Terry L. BuchmillerBoston Children’s Hospital and Harvard Medical School.United States Journal of Pediatric SurgeryJ Pediatr Surg 2022; 57: 195-198DOI: 10.1016/j.jpedsurg.2021.10.044 AbstractAim of study: Congenital Diaphragmatic Hernia (CDH) is associated with lung hypoplasia and pulmonary hypertension. Many patients receive care in

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Chest computed tomography findings of ground-glass nodules with enhancing central vessel/nodule in pediatric patients with BMPR2 mutations and plexogenic arteriopathy

Jason P. Weinman, David A. Mong, LaDonna J. Malone, D. Dunbar Ivy, Robin R. Deterding, Csaba GalambosChildren’s Hospital Colorado.United States Pediatric RadiologyPediatr Radiol 2022; 52: 2549-2556DOI: 10.1007/s00247-022-05413-8 AbstractBackground: Germline mutation in bone morphogenetic protein type II (BMPR2) is the most common cause of idiopathic/heritable pulmonary hypertension in pediatric patients. Despite the discovery of this gene there are

Chest computed tomography findings of ground-glass nodules with enhancing central vessel/nodule in pediatric patients with BMPR2 mutations and plexogenic arteriopathy Read More »

A novel non-invasive and echocardiography-derived method for quantification of right ventricular pressure-volume loops

Manuel J. Richter, Athiththan Yogeswaran, Faeq Husain-Sved, Istvan Vadasc, Zvomimir Rako, Emad Mojajerani, Hossein A. Ghofrani, Robert Naeije, Werner Seeger, Ulrike Herberg, Andreas Rieth, Ryan J. Tedford, Friedrich Grimminger, Henning Gall, Khodr TelloJustus-Liebig-University Giessen. Kerckhoff Heart, Rheuma and Thoracic Center. Imperial College London. Erasme University Hospital. University of Bonn. Medical University of South Carolina. Germany,

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Benefit of stereoscopic volume rendering for the identification of pediatric pulmonary vein stenosis from CT angiography

Michelle Noga, Ross Cockburn, Jiali Luan, Deepa Krishnaswamy, Kumaradevan PunithakumarUniversity of Alberta. Mazankowski Alberta Heart Institute. University of Manitoba. Dalhousie University.Canada PLOS Digital HealthPLOS Digit Health 2023; 2: DOI: 10.1371/journal.pdig.0000215 AbstractThe use of three-dimensional (3D) technologies in medical practice is increasing; however, its use is largely untested. One 3D technology, stereoscopic volume-rendered 3D display, can improve

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Factors associated with discontinuation of pulmonary vasodilator therapy in children with bronchopulmonary dysplasia-associated pulmonary hypertension

Catherine M. Avitabile, Xuemei Zhang, Steve B. Ampah, Yan Wang, Devon Ash, Kathleen Nilan, Laura Mercer-Rosa, Julie L. Fierro, David B. Frank, Kathleen A. GibbsUniversity of Pennsylvania and Children’s Hospital of Philadelphia.United States Journal of PerinatologyJ Perinatol 2022; 42: 1246-1254DOI: 10.1038/s41372-022-01421-6 AbstractObjective: To evaluate factors associated with discontinuation of pulmonary vasodilator therapy in bronchopulmonary dysplasia-related pulmonary hypertension

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Late onset of pulmonary hypertension in very low birth weight infants

Joseph Ginski, Dmitry Tumin, Devon Kuehn, Jason Higginson, Scott MacGilvrayEast Carolina UniversityUnited States Journal of Maternal Fetal and Neonatal MedicineJ Matern Fetal Neonatal Med 2022; 35: 3516-3518DOI: 10.1080/14767058.2020.1826924 AbstractIntroduction: Pulmonary hypertension (PH) is a recognized complication of bronchopulmonary dysplasia (BPD). Recent guidelines recommend evaluating all infants with BPD for PH via echocardiogram, but the specific timing of this screening

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