Diagnostic Testing for Pulmonary Vascular Disease. Non-invasive Testing

Physical Activity Measured by Hip-Anchored Accelerometry in Pediatric Pulmonary Hypertension: Association with Disease Severity & Estimation of Minimal Important Differences

Mark-Jan Ploegstra, Rosaria J. Ferreira, Chantal Lokhorst, Eva Gouwy, Suzanne S. J. Schwartz, Marlies G. Haarman, Matthieu Villeneuve, Dimitri Stamatiadis, Johannes M. Douwes, Rolf M. F. BergerBeatrix Children’s Hospital, University Medical Center Groningen andUniversity of Groningen. Actelion Pharmaceuticals.Netherlands and Switzerland ChestChest 2025; DOI: 10.1016/j.chest.2025.01.038 AbstractBackground: Pediatric pulmonary hypertension (PH) is a severe incurable disease with poor prognosis. […]

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Detection of pulmonary hypertension in preterm infants with bronchopulmonary dysplasia using oxygen saturation data

Pravitha Ramanand, Premananda Indic, Samuel J. Gentle, Namasivayam AmbalavananUniversity of Texas at Tyler. University of Alabama at Birmingham.United States Pediatric ResearchPediatr Res 2025; DOI: 10.1038/s41390-025-03891-8 AbstractBackground: Pulmonary hypertension (PH) complicates the clinical course of bronchopulmonary dysplasia (BPD) in preterm infants, increasing risk of mortality and other morbidities. Early detection of PH may provide the clinical opportunity for

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Inhalation of the Novel Tryptophan Hydroxylase 1 Inhibitor TPT-004 Alleviates Pulmonary Arterial Hypertension in Rats

Ekaterina Legchenko, Philippe Chouvarine, Klea Hysko, Fatimunnisa Qadri, Radoslw Wesolowski, Edgar Specker, Silke Glage, Martin Meier, Katharina Schwarz, Joerg Heineke, Gerhard Pohlmann, Mehmet Ramazanoglu, Michael Bader, Georg HansmannHannover Medical School. Heidelberg University Medical Faculty Mannheim. Max-Delbrück-Center for Molecular Medicine. Leibniz-Forschungsinstitut für Molekulare Pharmakologie. Fraunhofer Institute for Toxicology and Experimental Medicine. Max Delbrück Center for Molecular

Inhalation of the Novel Tryptophan Hydroxylase 1 Inhibitor TPT-004 Alleviates Pulmonary Arterial Hypertension in Rats Read More »

Characterization of Intracardiac Flow in the Right Ventricle With Pressure and Volume Overload in Children

Yasunobu Hayabuchi, Yukako HommaTokushima University.Japan Cardiology ResearchCardiol Res 2025; 16: 22-32DOI: 10.14740/cr2009 AbstractBackground: Blood flow visualization using vector flow mapping (VFM) holds potential as a novel indicator of right ventricular (RV) function.Methods: This study included 12 patients with atrial septal defect (ASD group, mean (± standard deviation) age: 6.2 ± 1.5 years), six patients with pulmonary hypertension (PH

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Pulmonary Morbidity in Congenital Diaphragmatic Hernia Survivors Treated at a Non-ECMO Center From 1998 to 2015: A Cross-Sectional Study

Ulla Lei Larsen, Lone Agertoft, Anne Maria Herskind, Thomas Strøm, Palle Toft, Susanne HalkenOdense University Hospital. University of Southern Denmark. H.C. Andersen Children’s Hospital. Hospital Sønderjylland.Denmark Pediatric PulmonologyPediatr Pulmonol 2025; 60: DOI: 10.1002/ppul.27468 AbstractIntroduction: A main feature of CDH is lung hypoplasia and the related presentation of pulmonary hypertension and cardiac dysfunction. Multiple factors influence pulmonary status

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The Role of Imaging in Pulmonary Vascular Disease: The Clinician’s Perspective

Brandon R. Jakubowski, Megan Griffiths, Kara N. GossUniversity of Texas Southwestern Medical Center.United States Radiology Clinics of North AmericaRadiol Clin North Am 2025; 63: 305-313DOI: 10.1016/j.rcl.2024.07.008 AbstractPulmonary vascular diseases, particularly when accompanied by pulmonary hypertension, are complex disorders often requiring multimodal imaging for diagnosis and monitoring. Echocardiography is the primary screening tool for pulmonary hypertension, while

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The prediction value of serum anion gap for short-term mortality in pulmonary hypertension patients with sepsis: a retrospective cohort study

Jinhua Zhu, Zeying Zhang, Yefei Lei, Zhenrong Ouyang, Shelby Kutty, Qiming Liu, Yunbin XiaoFirst People’s Hospital of Chenzhou and Hunan Children’s Hospital Affiliated to Jinan University. Xiamen Cardiovascular Hospital of Xiamen University. Johns Hopkins School of Medicine. Second Xiangya Hospital and Affiliated Children’s Hospital of Central South University. China Frontiers in MedicineFront Med 2025; 11: DOI: 10.3389/fmed.2024.1499677 AbstractBackground: The

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Mortality Prediction in Newborns With Persistent Pulmonary Hypertension: A Comparison of Four Illness Severity Scores

Pattima Pakhathirathien, Gunlawadee Maneenil, Anucha Thatrimontrichai, Supaporn Dissaneevate, Manapat PaditaukritPrince of Songkla University.Thailand Pediatric PulmonologyPediatr Pulmonol 2025; 60: DOI: 10.1002/ppul.27484 AbstractObjective: This study aimed to compare the accuracy of four neonatal illness severity scores for predicting mortality in persistent pulmonary hypertension of the newborn (PPHN).Study design: This retrospective study included neonates diagnosed with PPHN between 2013 and 2022.

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Conservative Pulmonary Arteriovenous Malformation Screening in Children: Re-Evaluation of Safety

Fleur ten Berg, Josefien Hessels, Anna Hosman, Sanne Boerman, Marco C. Post, Walter A. F. Balemans, Hans-Jurgen MagerSt. Antonius Hospital. University Medical Centre Utrecht. Netherlands Pediatric PulmonologyPediatr Pulmonol 2025; 60: DOI: 10.1002/ppul.27476 AbstractIntroduction: Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant vascular disease and screening to detect pulmonary arteriovenous malformations (PAVMs) is important to prevent complications. In

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Congenital pulmonary vein stenosis: a radiographic study

Christopher K. Adey, Benigno Soto, Myung S. ShinUniversity of Alabama School of MedicineUnited States RadiologyRadiology 1986; 161: 113-117DOI: 10.1148/radiology.161.1.3763853 AbstractSeven patients with congenital pulmonary venous stenosis were retrospectively evaluated. Chest radiographs and pulmonary angiograms were interpreted without knowledge of anatomic findings, and results were correlated with autopsy data. Bilateral foci of stenosis of varying severity were

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