Diagnostic Testing for Pulmonary Vascular Disease. Non-invasive Testing

Computed tomographic parenchymal lung findings in premature infants with pulmonary vein stenosis

Barry O’Callaghan, Jenny E. Zablah, Jason P. Weinman, Erin K. Englund, Gareth J. Morgan, D. Dunbar Ivy, Benjamin S. Frank, David Andrew Mong, LaDonna J. Malone, Lorna P. BrowneChildren’s Hospital Colorado, Aurora and University of Colorado Medical SchoolUnited States Pediatric RadiologyPediatr Radiol 2023; DOI: 10.1007/s00247-023-05673-y AbstractBackground: Developmental pulmonary vein pulmonary vein stenosis in the setting of prematurity […]

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Echocardiographic Markers of Mild Pulmonary Hypertension are not Correlated with Worse Respiratory Outcomes in Infants with Bronchiolitis

Maria Lucia Rossi, Maria Clara Escobar-Diaz, Stephanie Marie Hadley, Paula Cecilia Randanne, Joan Sanchez-de-Toledo, Iolanda JordanSant Joan de Deu Hospital. Sant Joan de Déu Research Institute. Boston Children’s Hospital. University of Pittsburgh. University of Barcelona. Consorcio de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERESP)Spain and United States Pediatric CardiologyPediatr Cardiol 2023; 44:

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Treprostinil in Neonates with Congenital Diaphragmatic Hernia-Related Pulmonary Hypertension

Felix R. De Bie, Catherine M. Avitabile, Sabrina Flohr, Sierra Land, Leny Mathew, Yan Wang, Devon Ash, Natalie E. Rintoul, Holly L. HedrickChildren’s Hospital of Philadelphia and University of Pennsylvania Perelman School of Medicine. Cluster Woman and Child. United States and Belgium Journal of PediatricsJ Pediatr 2023; DOI: 10.1016/j.jpeds.2023.113420 AbstractObjective: To describe our experience with treprostinil, evaluate

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Monitoring of Hemodynamics With Right Heart Catheterization in Children With Pulmonary Arterial Hypertension

Julien Grynblat, Sophie-Guiti Malekzadeh-Milani, Mathilde Meot, Frédéric Perros, Isabelle Szezepanski, Stéphane Morisset, Caroline Ovaert, Caroline Bonnet, Pascale Maragnes, Julien Ranchoup, Marc Humbert, I. David Montani, Marilyne Levy, Damien BonnetM3C-Necker, Hôpital Necker-Enfants malades and AP-HP Université de Paris Cité. Université Paris-Saclay. Hôpital Marie Lannelongue Le Plessis. AP-HP Hôpital Bicêtre. La Timone Hospital. Caen University. CHU. France

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Prognostic Value of Transthoracic Echocardiography in Children With Pulmonary Arterial Hypertension

Astrid E. Lammers, Jan Marek, Gerhard-Paul Diller, Sheila G. Haworth, Shahin MoledinaGreat Ormond Street Hospital for Children. Muenster University Hospital. University College London.United Kingdom and Germany Journal of the American Heart AssociationJ Am Heart Assoc 2023; 12: DOI: 10.1161/JAHA.121.023118 AbstractBackground Transthoracic echocardiography is part of the regular follow-up protocol at most pediatric pulmonary arterial hypertension (PAH)

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A scoping review of echocardiographic and lung ultrasound biomarkers of bronchopulmonary dysplasia in preterm infants

Silvia Martini, Iuri Corsini, Luigi Corvaglia, Pradeep Suryawanshi, Belinda Chan, Yogen SinghUniversity of Bologna. Careggi University Hospital of Florence. Bharati Vidyapeeth University Medical College. University of Utah. Loma Linda University School of Medicine. Cambridge University Hospitals. Italy, United States and United Kingdom Frontiers in PediatricsFront Pediatr 2023; 11: DOI: 10.3389/fped.2023.1067323 AbstractDespite recent improvements in neonatal care,

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Targeted neonatal echocardiography and lung ultrasound in preterm infants with chronic lung disease with and without pulmonary hypertension, screened using a standardized algorithm

Janneth Cristina Sánchez-Becerra, Rogelio Guillén-Torres, Rosario Becerra-Becerra, Horacio Márquez-González, Daniel Ibarra-RíosNational Institute of Health and Hospital Infantil de México Federico Gómez.Mexico Frontiers in PediatricsFront Pediatr 2023; 11: DOI: 10.3389/fped.2023.1104940 AbstractIntroduction: Increased recognition of the development of chronic pulmonary hypertension (cPH) in preterm infants with chronic lung disease (CLD) has prompted enhanced monitoring for the identification of different

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Pathogenic variants in MDFIC cause recessive central conducting lymphatic anomaly with lymphedema

Alicia B. Byrne, Pascal Brouillard, Drew L. Sutton, Jan Kazenwadel, Saba Montazaribarforoushi, Genevieve A. Secker, Anna Oszmiana, Milena Babic, Kelly L. Betterman, Peter J. Brautigan, Melissa White, Sandra G. Piltz, Paul Q. Thomas, Christopher N. Hahn, Matthias Rath, Ute Felbor, G. Christoph Korenke, Christopher L. Smith, Kathleen H. Wood, Sarah E. Sheppard, Denise M. Adams,

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MR lymphangiography of lymphatic abnormalities in children and adults with Noonan syndrome

C. C. Pieper, J. Wagenpfeil, A. Henkel, S. Geiger, T. Köster, K. Hoss, J. A. Luetkens, C. Hart, U. I. Attenberger, A. MüllerUniversity of Bonn and Children’s Hospital.Germany Scientific ReportsSci Rep 2022; 12: DOI: 10.1038/s41598-022-13806-w AbstractNoonan syndrome is associated with complex lymphatic abnormalities. We report dynamic-contrast enhanced MR lymphangiography (DCMRL) findings in children and adults with

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Lymphatic Phenotype of Noonan Syndrome: Innovative Diagnosis and Possible Implications for Therapy

Lotte E. R. Kleimeier, Carolinevan Schaik, Erika Leenders, Maxim Itkin, Willemijn M. Klein, Jos M. T. DraaismaRadboudumc Amalia Children’s Hospital and Radboud University Medical Center. University of Pennsylvania.Netherlands and United States Journal of Clinical MedicineJ Clin Med 2022; 11: DOI: 10.3390/jcm11113128 AbstractDysregulation of the Ras/Mitogen-activated protein kinase (MAPK) signaling pathway is suggested to play a pivotal

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