Diagnostic Testing for Pulmonary Vascular Disease. Non-invasive Testing

Echocardiographic Assessment of Pulmonary Arterial Hypertension Following Inhaled Nitric Oxide in Infants with Severe Bronchopulmonary Dysplasia

Maria V. Fraga, Kevin C. Dysart, Jason Z. Stroller, Matthew Huber, Anysia Fedec, Laura Mercer-Rosa, Haresh KirpalaniThe Children’s Hospital of Philadelphia and University of Pennsylvania Perelman School of Medicine. Nemours Children’s Health and duPont Hospital for Children. McMaster University.United States and Canada NeonatologyNeonatology 2023; DOI: 10.1159/000531586 AbstractObjectives: Inhaled nitric oxide (iNO) is an effective pulmonary vasodilator. However, […]

Echocardiographic Assessment of Pulmonary Arterial Hypertension Following Inhaled Nitric Oxide in Infants with Severe Bronchopulmonary Dysplasia Read More »

Diastolic ventricular function in persistent pulmonary hypertension of the newborn

Kévin Le Duc, Thameur Rakza, Jean Benoit Baudelet, Mohamed Riadh Boukhris, Sébastien Mur, Ali Houeijeh, Laurent StormePôle Femme-Mère-Nouveau-Né, Hôpital Jeanne de Flandre, Centre Hospitalier Universitaire de Lille and University of Lille. France Frontiers in PediatricsFront Pediatr 2023;DOI: 10.3389/fped.2023.1175178 AbstractBackground: Persistent pulmonary hypertension of the newborn (PPHN) is usually considered a consequence of impaired pulmonary circulation. However, little

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Clinical relevance of rapid FOXF1-targeted sequencing in patients suspected of alveolar capillary dysplasia with misalignment of pulmonary veins

Gabriëla G. Edel, Janna A. Hol, Evelien Slot, Jan H. von der Thüsen, Yolande van Bever, Rogier C.J. de Jonge, Marianne van Tienhoven, Hennie T. Bruggenwirth, Annelies de Klein, Robbert J. RottierErasmus MC Sophia Children’s Hospital. Netherlands Laboratory InvestigationLab Invest 2023; DOI: 10.1016/j.labinv.2023.100233 AbstractAlveolar capillary dysplasia with misalignment of pulmonary Veins (ACDMPV) is a lethal congenital

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Identification of ACKR4 as an immune checkpoint in pulmonary arterial hypertension

Chen-Yu Jiang, Li-Wei Wu, Yi-Wei Liu, Bei Feng, Lin-Cai Ye, Xu Huang, Yang-Yang He, Yi Shen, Yi-Fan Zhu, Xing-Liang Zhou, Dai-Ji Jiang, Hai-Kun Qi, Hao Zhang, Yi YanShanghai Children’s Medical Center. Henan University. Shanghaitech University. China Frontiers in ImmunologyFront Immunol 2023; DOI: 10.3389/fimmu.2023.1153573 AbstractObjective: Inflammation is recognized as a contributor in the development of pulmonary arterial hypertension

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Can Speckle Tracking Of Right Ventricle Add Value For Evaluation Of Asthma Severity In Children?

Ahmed Mohammad Abbas, Hany Hussein Mousa, Reda Biomy Bastawesy, Osama ElagamyKafrelsheikh University.Egypt Journal of the Pakistan Medical AssociationJ Pak Med Assoc 2023; 73(Suppl 4): S156-S160DOI: 10.47391/JPMA.EGY-S4-32 AbstractObjectives: To investigate myocardial deformation by tracking speckles along with evaluation of cardiac function using conventional and tissue Doppler imaging.Method: The case-control study was conducted at Kafrelsheikh University Hospital, Egypt, from September

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Pulmonary Hypertension and Left Ventricular Geometric Types in Sickle Cell Anemia

Opeyemi Olalekan Oni, Abiona Oluwadamilola Odeyemi, Tetende Toyin Olasinde, Abimbola Ololade Odayemi, Kehinde Joyce Olufemi-Aworinde, Ademola Toyosi Abolarin, Oluwabukola Ayodele AlaLAUTECH University. Osun State University.  Bowen University. Nigeria American Journal of CardiologyAm J Cardiol 2023; 203: 175-183DOI: 10.1016/j.amjcard.2023.06.100 AbstractPulmonary hypertension (PHT) is multifactorial in origin and a major cause of morbidity and mortality in the sickle

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Deriving Convergent and Divergent Metabolomic Correlates of Pulmonary Arterial Hypertension

Mona Alotaibi, Yunxian Liu, Gino A. Magalang, Alan C. Kwan, Joseph E. Ebinger, William C. Nichols, Michael W. Pauciulo, Mohit Jain, Susan ChengUniversity of California San Diego. Cedars-Sinai Medical Center. University of Cincinnati and Cincinnati Children’s Hospital Medical Center.United States MetabolitesMetabolites 2023; 13DOI: 10.3390/metabo13070802 AbstractHigh-dimensional metabolomics analyses may identify convergent and divergent markers, potentially representing aligned

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Assessment of Myocardial Function in Infants of Mothers with Gestational Diabetes Mellitus using Deformation Imaging over the First Year of Age

Aisling Smith, Orla Franklin Mrcpch, Naomi McCallion, Fionnuala Breathnach, Afif El-KhuffashThe Rotunda Hospital. Our Lady’s Children’s Hospital Crumlin. The Royal College of Surgeons in Ireland.Ireland Journal of PediatricsJ Pediatr 2023; DOI: 10.1016/j.jpeds.2023.113645 AbstractObjective: To assess serial myocardial performance and pulmonary vascular resistance (PVR) in infants of mothers with gestational diabetes mellitus (GDM) over the first year of

Assessment of Myocardial Function in Infants of Mothers with Gestational Diabetes Mellitus using Deformation Imaging over the First Year of Age Read More »

Three-Dimensional, Right Ventricular Surface Strain Computation From Three Dimensional Echocardiographic Images From Patients With Pediatric Pulmonary Hypertension

Priyamvada Kundu, Michal Schafer, Lisa Le, Thomas Thomas, Pei-Ne Jone, Kendall HunterChildren’s Hospital Colorado. Ann and Robert H. Lurie Children’s Hospital of Chicago.United States Journal of Biomechanical EngineeringJ Biomech Eng 2023; DOI: 10.1115/1.4063121 AbstractBackground: Right Ventricular (RV) dysfunction is routinely assessed with echocardiographic-derived global longitudinal strain (GLS). GLS is measured from a two-dimensional echo (2DE) image and

Three-Dimensional, Right Ventricular Surface Strain Computation From Three Dimensional Echocardiographic Images From Patients With Pediatric Pulmonary Hypertension Read More »

Measurement of Physical Activity by Actigraphy in Infants and Young Children with Pulmonary Arterial Hypertension

Catherine M. Avitabile, Delphine Yung, Stephanie Handler, Rachel K. Hopper, Jeff Fineman, Grace Freire, Nidhy Varghese, Mary Mullen, Usha S. Krishnan, Eric Austin, Lori Silveira, D. Dunbar IvyChildren’s Hospital of Philadelphia and University of Pennsylvania Perelman School of Medicine. University of Washington School of Medicine. Medical College of Wisconsin. Stanford University School of Medicine. University

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