Diagnostic Testing for Pulmonary Vascular Disease. Non-invasive Testing

The cascade screening in heritable forms of pulmonary arterial hypertension

Nidhy P. Varghese, Akhilesh A. Padhye, Pilar L. Magoulas, George B. Mallory, Fadel E. Ruiz, Sandeep SahayBaylor College of Medicine Texas Children’s Hospital Houston. Houston Methodist Hospital. Weill Cornell Medical College.United States Pulmonary CirculationPulm Circ 2023;DOI: 10.1002/pul2.12259 AbstractHeritable pulmonary artery hypertension (HPAH) is an increasingly recognized type of pulmonary arterial hypertension, in both pediatric and adult […]

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Ventricular global function index is associated with clinical outcomes in pediatric pulmonary hypertension

Hieu T. Ta, Paul J. Critser, Michal Schäfer, Nicholas J. Ollberding, Michael D. Taylor, Michael V. Di Maria, Russel Hirsch, D. Dunbar Ivy, Benjamin S. FrankCincinnati Children’s Hospital Medical Center and University of Cincinnati. University of Colorado. United States Journal of Cardiovascular Magnetic ResonanceJ Cardiovasc Magnet Reson 2023; 25DOI: 10.1186/s12968-023-00947-8 AbstractBackground: Multiple right ventricular (RV) metrics have

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Low incidence of pulmonary hypertension in children with suspected obstructive sleep apnea: A prospective observational study

Khadar A. Omer, Raphael Mlauzi, Wisdom Basera, Jessica McGuire, Heidi Meyer, John Lawrenson, Shazia Peer, Yanita Singh, Marco ZampoliUniversity of Cape Town and Red Cross War Memorial Children’s Hospital.South Africa International Journal of Pediatric OtorhinolaryngologyInt J Pediatr Otorhinolaryngol 2023; DOI: 10.1016/j.ijporl.2023.111648 AbstractObjectives: Pulmonary hypertension (PH) secondary to obstructive sleep apnea (OSA) is an uncommon but serious perioperative

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Echocardiographic Assessment of Pulmonary Arterial Hypertension Following Inhaled Nitric Oxide in Infants with Severe Bronchopulmonary Dysplasia

Maria V. Fraga, Kevin C. Dysart, Jason Z. Stroller, Matthew Huber, Anysia Fedec, Laura Mercer-Rosa, Haresh KirpalaniThe Children’s Hospital of Philadelphia and University of Pennsylvania Perelman School of Medicine. Nemours Children’s Health and duPont Hospital for Children. McMaster University.United States and Canada NeonatologyNeonatology 2023; DOI: 10.1159/000531586 AbstractObjectives: Inhaled nitric oxide (iNO) is an effective pulmonary vasodilator. However,

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Diastolic ventricular function in persistent pulmonary hypertension of the newborn

Kévin Le Duc, Thameur Rakza, Jean Benoit Baudelet, Mohamed Riadh Boukhris, Sébastien Mur, Ali Houeijeh, Laurent StormePôle Femme-Mère-Nouveau-Né, Hôpital Jeanne de Flandre, Centre Hospitalier Universitaire de Lille and University of Lille. France Frontiers in PediatricsFront Pediatr 2023;DOI: 10.3389/fped.2023.1175178 AbstractBackground: Persistent pulmonary hypertension of the newborn (PPHN) is usually considered a consequence of impaired pulmonary circulation. However, little

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Clinical relevance of rapid FOXF1-targeted sequencing in patients suspected of alveolar capillary dysplasia with misalignment of pulmonary veins

Gabriëla G. Edel, Janna A. Hol, Evelien Slot, Jan H. von der Thüsen, Yolande van Bever, Rogier C.J. de Jonge, Marianne van Tienhoven, Hennie T. Bruggenwirth, Annelies de Klein, Robbert J. RottierErasmus MC Sophia Children’s Hospital. Netherlands Laboratory InvestigationLab Invest 2023; DOI: 10.1016/j.labinv.2023.100233 AbstractAlveolar capillary dysplasia with misalignment of pulmonary Veins (ACDMPV) is a lethal congenital

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Identification of ACKR4 as an immune checkpoint in pulmonary arterial hypertension

Chen-Yu Jiang, Li-Wei Wu, Yi-Wei Liu, Bei Feng, Lin-Cai Ye, Xu Huang, Yang-Yang He, Yi Shen, Yi-Fan Zhu, Xing-Liang Zhou, Dai-Ji Jiang, Hai-Kun Qi, Hao Zhang, Yi YanShanghai Children’s Medical Center. Henan University. Shanghaitech University. China Frontiers in ImmunologyFront Immunol 2023; DOI: 10.3389/fimmu.2023.1153573 AbstractObjective: Inflammation is recognized as a contributor in the development of pulmonary arterial hypertension

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Can Speckle Tracking Of Right Ventricle Add Value For Evaluation Of Asthma Severity In Children?

Ahmed Mohammad Abbas, Hany Hussein Mousa, Reda Biomy Bastawesy, Osama ElagamyKafrelsheikh University.Egypt Journal of the Pakistan Medical AssociationJ Pak Med Assoc 2023; 73(Suppl 4): S156-S160DOI: 10.47391/JPMA.EGY-S4-32 AbstractObjectives: To investigate myocardial deformation by tracking speckles along with evaluation of cardiac function using conventional and tissue Doppler imaging.Method: The case-control study was conducted at Kafrelsheikh University Hospital, Egypt, from September

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Pulmonary Hypertension and Left Ventricular Geometric Types in Sickle Cell Anemia

Opeyemi Olalekan Oni, Abiona Oluwadamilola Odeyemi, Tetende Toyin Olasinde, Abimbola Ololade Odayemi, Kehinde Joyce Olufemi-Aworinde, Ademola Toyosi Abolarin, Oluwabukola Ayodele AlaLAUTECH University. Osun State University.  Bowen University. Nigeria American Journal of CardiologyAm J Cardiol 2023; 203: 175-183DOI: 10.1016/j.amjcard.2023.06.100 AbstractPulmonary hypertension (PHT) is multifactorial in origin and a major cause of morbidity and mortality in the sickle

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Deriving Convergent and Divergent Metabolomic Correlates of Pulmonary Arterial Hypertension

Mona Alotaibi, Yunxian Liu, Gino A. Magalang, Alan C. Kwan, Joseph E. Ebinger, William C. Nichols, Michael W. Pauciulo, Mohit Jain, Susan ChengUniversity of California San Diego. Cedars-Sinai Medical Center. University of Cincinnati and Cincinnati Children’s Hospital Medical Center.United States MetabolitesMetabolites 2023; 13DOI: 10.3390/metabo13070802 AbstractHigh-dimensional metabolomics analyses may identify convergent and divergent markers, potentially representing aligned

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