Class 4. Pulmonary Hypertension Associated with Thromboembolic Disease

Massive pulmonary thromboembolism in an adolescent with SARS-CoV-2 infection

Verónica Chauriye Kuncar, Cecilia Castillo Acevedo, Carlos Acuña Aguirre, Piaignacia Díaz EspejoHospital Luis Calvo Mackenna.Chile Archivos Argentinos De PediatriaArch Argent Pediatr 2024; DOI: 10.5546/aap.2024-10474.eng AbstractThromboembolic events incidence is low in pediatrics; high suspicion and explicit management algorithms are essential. We present a 12-year-old female patient with two weeks of dyspnea, orthopnea, and ankle edema. Tests showed […]

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Circulating Endothelin 1 but Not Transforming Growth Factor-β Levels Are Reduced after Pulmonary Endarterectomy in Subjects Affected by Chronic Thromboembolic Pulmonary Hypertension: A Prospective Cohort Study

Pasquale Totaro, Claudio Tirelli, Lucia Sacchi, Annalisa De Silvestri, Mara DeAmici, Fabrizio Grosjean, Giorgia Testa, Alessia Alloni, Eraldo Kushta, Riccardo Albertini, Teresa Rampino, Andrea Maria D’ArminiFoundation I.R.C.C.S. Policlinico San Matteo. University of Milan. University of Pavia. Italy Journal of Clinical MedicineJ Clin Med 2024; DOI: 10.3390/jcm13174977 AbstractBackground and objectives: Endothelin-1 (ET-1) and transforming growth factor-β (TGF-β) play

Circulating Endothelin 1 but Not Transforming Growth Factor-β Levels Are Reduced after Pulmonary Endarterectomy in Subjects Affected by Chronic Thromboembolic Pulmonary Hypertension: A Prospective Cohort Study Read More »

Chronic thromboembolic pulmonary disease: Association with exercise-induced pulmonary hypertension and right ventricle adaptation over time: Chronic thromboembolic pulmonary disease and exercise pulmonary hypertension

Rosalinda Madonna, Mattia Alberti, Filippo Biondi, Riccardo Morganti, Roberto Badagliacca, Carmine Dario Vizza, Raffaele De CaterinaPisa University Hospital and University of Pisa. Sapienza University.Italy European Journal of Internal MedicineEur J Intern Med 2023; DOI: 10.1016/j.ejim.2023.11.021 AbstractBackground and aim: Chronic thromboembolic pulmonary disease (CTEPD) is a progressive condition caused by fibrotic thrombi and vascular remodeling in the pulmonary

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Recurrent Syncope Unveiling Pulmonary Hypertension Secondary to Pulmonary Artery Thrombi in a Pediatric Patient

Dina AlkhateebAltamimi, Karim Khalidi, Rima Khasawneh, Abdulhadi Alzaben, Khaled SalaymehAl Khalidi Hospital. Yarmouk University. Jordan CureusCureus 2024; 16DOI: 10.7759/cureus.51812 AbstractWe present a case of a nine-year-old female patient who presented with recurrent syncope and was ultimately diagnosed with pulmonary hypertension (PH) secondary to pulmonary artery thrombi in the context of anti-phospholipid syndrome (APS). Extensive investigations including

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A rare presentation of childhood interstitial lung disease attributed to KDM3B gene mutation: a case report

Zaineb Benslimane, Sinan Yavuz, Nader FrancisAl Qassimi Women and Children Hospital.United Arab Emirates PanAfrican Medical JournalPan Afr Med J 2023; 46DOI: 10.11604/pamj.2023.46.84.41457 AbstractChildhood Interstitial Lung Disease (chILD) encompasses various respiratory conditions affecting children’s lung airspaces and tissues, with diverse causes. One rare cause involves structural vascular changes. We describe a case of a 10-year-old boy diagnosed

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Case report: Central venous catheter thrombosis complicated by chronic thromboembolic disease/pulmonary hypertension in two children requiring parenteral nutrition

Maja Hanuna, Joseph Pattathu, Joscha Buech, Christine Kamla, Nikolaus Kneidinger, Juergen Behr, Katrin Milger, Tobias Veit, Marina Nagel, Jan Abicht, Robert Dalla-Pozza, Marcus Fischer, Andre Jakob, Matthias Hermann, Rene Schramm, Laura L. Rosenthal, Nikolaus Haas, Jürgen Hörer, Christian Hagl, Sebastian G. MichelLudwig Maximilian University Munich. Munich Heart Alliance. Comprehensive Pneumology Center Munich. Heart and Diabetes

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Spontaneous neonatal pulmonary arterial thrombosis – cases, mechanisms, and literature review

Ali Abdelhafiz, Alexis L. Benscoter, Sarosh P. BatlivalaCincinnati Children’s Hospital Medical Center and University of Cincinnati College of Medicine.United States Cardiology in the YoungCardiol Young 2023; DOI: 10.1017/S1047951123002639 AbstractSpontaneous pulmonary artery thrombosis in neonates is rare and can be life-threatening. Clinical presentation may mimic pulmonary hypertension or CHD. Further, not all children present with identifiable risk

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Single-Cell Analysis Reveals Distinct Immune and Smooth Muscle Cell Populations that Contribute to Chronic Thromboembolic Pulmonary Hypertension

Gayathri Viswananthan, Helene Fradin Kirshner, Nour Nazo, Saba Ali, Asvin Ganapathi, Ian Cumming, Youghua Zhuang, Issac Choi, Anmol Warman, Chanpreet Jassal, Susana Almeida-Peters, John Haney, David Corcoran, Yen-Rei Yu, Sudarshan RajagopalUniversity of Colorado Anschutz Medical Campus. Duke University School of Medicine.United States American Journal of Respiratory and Critical Care MedicineAm J Respir Crit Care Med

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Characterizing the Spatiotemporal Transcriptomic Response of the Right Ventricle to Acute Pressure Overload

Vitaly O. Kheyfets, Sushil Kumar, Paul M. Heerdt, Kenzo Ichimura, R. Dale Brown, Melissa Lucero, Ilham Essafri, Sarah Williams, Kurt R. Stenmark, Edda SpiekerkoetterUniversity of Colorado. Yale School of Medicine. Stanford University. he University of Queensland.United States and Australia International Journal of Molecular SciencesInt J Mol Sci 2023; 24: DOI: 10.3390/ijms24119746 AbstractThis study analyzed microarray data

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Acute vasoreactivity testing during right heart catheterization in chronic thromboembolic pulmonary hypertension: Results from the pulmonary vascular disease phenomics study

Robert P. Frantz, Jane A. Leopold, Paul M. Hassoun, Anna R. Hemnes, Evelyn M. Horn, Stephen C. Mathai, Franz P. Rischard, A. Brett Larive, W.h. Wilson Tang, Margaret M. Park, Nicholas S. Hill, Erika B. RosenzweigMayo Clinic. Harvard Medical School. Johns Hopkins University. Vanderbilt University Medical Center. Weill Cornell Medicine. Cleveland Clinic. Tufts Medical Center.

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