Class 3. Pulmonary Hypertension Associated with Lung Disease

Outpatient respiratory outcomes in children with BPD on supplemental oxygen

Julianne R. McGlynn, Brianna C. Aoyama, Amanda Martin, Joseph M. Collaco, Sharon A. McGrath-MorrowChildren’s Hospital of Philadelphia and University of Pennsylvania. Johns Hopkins University School of Medicine.United States Pediatric PulmonologyPediatr Pulmonol 2023; 58: 1535-1541DOI: 10.1002/ppul.26356 AbstractIntroduction: Preterm children with bronchopulmonary dysplasia (BPD) frequently require supplemental oxygen in the outpatient setting. In this study, we sought to determine […]

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Inhaled nitric oxide in preterm neonates with preterm prelabour rupture of membranes, a systematic review

Rachel Mullaly, Naomi McCallion, Afif El-KhuffashThe Rotunda Hospital. University of Southampton. Royal College of Surgeons of Ireland.Ireland and United Kingdom Acta PediatricaActa Pediar 2023; 112: 358-371DOI: 10.1111/apa.16596 AbstractAim: To perform a systematic literature review to determine the effect of inhaled nitric oxide (iNO) on oxygenation, mortality and morbidity in preterm neonates with preterm prelabour rupture of membranes

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Echocardiographic Markers of Mild Pulmonary Hypertension are not Correlated with Worse Respiratory Outcomes in Infants with Bronchiolitis

Maria Lucia Rossi, Maria Clara Escobar-Diaz, Stephanie Marie Hadley, Paula Cecilia Randanne, Joan Sanchez-de-Toledo, Iolanda JordanSant Joan de Deu Hospital. Sant Joan de Déu Research Institute. Boston Children’s Hospital. University of Pittsburgh. University of Barcelona. Consorcio de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERESP)Spain and United States Pediatric CardiologyPediatr Cardiol 2023; 44:

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Lung biopsy in infants with severe bronchopulmonary dysplasia

Danielle A. Callaway, Yifei Wang, Krithika Lingappan, Jennifer E. Pogoriler, Pablo Laje, Kathleen Nilan, Haresh Kirpalani, Huayan ZhangThe Children’s Hospital of Philadelphia. Guangdong Provincial People’s Hospital. McMaster University. Guangzhou Women and Children’s Medical Center.United States, China and Canada Pediatric PulmonologyPediatr Pulmonol 2023; DOI: 10.1002/ppul.26433 AbstractIntroduction: Lung biopsy is infrequently performed in the population of infants with severe

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A scoping review of echocardiographic and lung ultrasound biomarkers of bronchopulmonary dysplasia in preterm infants

Silvia Martini, Iuri Corsini, Luigi Corvaglia, Pradeep Suryawanshi, Belinda Chan, Yogen SinghUniversity of Bologna. Careggi University Hospital of Florence. Bharati Vidyapeeth University Medical College. University of Utah. Loma Linda University School of Medicine. Cambridge University Hospitals. Italy, United States and United Kingdom Frontiers in PediatricsFront Pediatr 2023; 11: DOI: 10.3389/fped.2023.1067323 AbstractDespite recent improvements in neonatal care,

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Pathological Roles for Endothelial Colony-Forming Cells in Neonatal and Adult Lung Disease

Jason O. Robertson, Serpil C. Erzurum, Kewal AsosinghCleveland ClinicUnited States American Journal of Respiratory Cell and Molecular BiologyAm J Respir Cell Mol Biol 2023; 68: 13-22DOI: 10.1165/rcmb.2022-0318PS AbstractEndothelial colony-forming cells (ECFCs) are vascular resident and circulating endothelial cell subtypes with potent angiogenic capacity, a hierarchy of single-cell clonogenic potentials, and the ability to participate in de novo blood

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Vascular and pulmonary effects of ibuprofen on neonatal lung development

Xueyu Chen, Dongshan Han, Xuan Wang, Xuemei Huang, Zilu Huang, Yijun Liu, Junyan Zhong, Frans J. Walther, Chuanzhong Yang, Gerry T. M. WagenaarAffiliated Shenzhen Maternity and Child Healthcare Hospital, The First School of Clinical Medicine, Southern Medical University. David Geffen School of Medicine, University of California Los Angeles. Lundquist Institute for Biomedical Innovation at Harbor-UCLA

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Pulmonary Vascular Phenotypes of Prematurity: The Path to Precision Medicine

Hussnain Mirza, Erica Mandell, John P. Kinsella, Patrick J. McNamara, Steven H. Abmandvent Health for Children and UCF College of Medicine. University of Iowa School of Medicine. University of Colorado Anschutz School of Medicine and Children’s Hospital Colorado.United States Journal of PediatricsJ Pediatr 2023; DOI: 10.1016/j.jpeds.2023.113444 AbstractPulmonary hypertension (PH) is associated with significant morbidities and high

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The Role of the Interleukin-1 Family in Complications of Prematurity

Elys A. Green, Steven P. Garrick, Briana Peterson, Philip J. Berger, Robert Galinsky, Rod W. Hunt, Steven X. Cho, Jane E. Bourke, Marcel F. Nold, Claudia A. Nold-PetryHudson Institute of Medical Research. Monash University. Monash Children’s Hospital. Australia International Journal of Molecular SciencesInt J Mol Sci 2023; 24: DOI: 10.3390/ijms24032795 AbstractPreterm birth is a major contributor

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Evaluation of levosimendan as treatment option in a large case-series of preterm infants with cardiac dysfunction and pulmonary hypertension

Lukas Schroeder, Stanley Holcher, Judith Leyens, Annegret Geipel, Brigitte Strizek, Till Dresbach, Andreas Mueller, Florian KipfmuellerUniversity Children’s Hospital Bonn. University Hospital Bonn.Germany European Journal of PediatricsEur J Pediatr 2023; DOI: 10.1007/s00431-023-04971-9 AbstractLevosimendan as a calcium-sensitizer is a promising innovative therapeutical option for the treatment of severe cardiac dysfunction (CD) and pulmonary hypertension (PH) in preterm infants,

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