Class 3. Pulmonary Hypertension Associated with Lung Disease

Histologic features and decreased lung FOXF1 gene expression in severe bronchopulmonary dysplasia without a genetic diagnosis of alveolar capillary dysplasia

Csaba Galambos, J. Wells Logan, Pawel Stankiewicz, Przemyslaw Szafranski, Carol Zalles, Jose Gonzales, Sfurti Nath, Shalinkumar Patel, Steven H. AbmanUniversity of Colorado Anschutz School of Medicine. Wolfson Children’s Hospital and the University of Florida College of Medicine. Baylor College of Medicine.United States Pediatric PulmonologyPediatr Pulmonol 2023; DOI: 10.1002/ppul.26571 AbstractWe report the case of a preterm infant […]

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Severity of preterm birth and the risk of pulmonary hypertension in childhood: A population-based cohort study in Sweden

Hanna Carr, Anna Gunnerbeck, Peter Eisenlauer, Stefan Johansson, Sven Cnattingius, Jonas F. Ludvigsson, Anna-Karin Edstedt BonamyKarolinska Institutet and Karolinska University Hospital. Södersjukhuset. Örebro University Hospital.Sweden Pediatric and Perinatal EpidemiologyPediatr Perinat Epidemiol 2023; DOI: 10.1111/ppe.12997 AbstractBackground: Preterm birth (<37 completed gestational weeks) has been linked to pulmonary hypertension (PH), but the relationship to severity of preterm birth has

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The eNAMPT/TLR4 inflammatory cascade drives the severity of intra-amniotic inflammation in pregnancy and predicts infant outcomes

Mohamed Ahmed, Nancy G. Casanova, Nahla Zaghloul, Akash Gupta, Marisela Rodriguez, Ian R. Robbins, Carrie L. Kempf, Xiaoguang Sun, Jin H. Song, Vivian Reyes Hernon, Saad Sammani, Sara M. Camp, Alvaro Moreira, Chaur-Dong Hsu, Joe G. N. GarciaUniversity of Arizona Health Sciences. UT Health San Antonio Long School of Medicine. United States Frontiers in PhysiologyFront

The eNAMPT/TLR4 inflammatory cascade drives the severity of intra-amniotic inflammation in pregnancy and predicts infant outcomes Read More »

Echocardiographic Assessment of Pulmonary Arterial Hypertension Following Inhaled Nitric Oxide in Infants with Severe Bronchopulmonary Dysplasia

Maria V. Fraga, Kevin C. Dysart, Jason Z. Stroller, Matthew Huber, Anysia Fedec, Laura Mercer-Rosa, Haresh KirpalaniThe Children’s Hospital of Philadelphia and University of Pennsylvania Perelman School of Medicine. Nemours Children’s Health and duPont Hospital for Children. McMaster University.United States and Canada NeonatologyNeonatology 2023; DOI: 10.1159/000531586 AbstractObjectives: Inhaled nitric oxide (iNO) is an effective pulmonary vasodilator. However,

Echocardiographic Assessment of Pulmonary Arterial Hypertension Following Inhaled Nitric Oxide in Infants with Severe Bronchopulmonary Dysplasia Read More »

Transcatheter Ductus Arteriosus Stenting for Acute Pediatric Pulmonary Arterial Hypertension is Associated with Improved Right Ventricular Echocardiography Strain

Jason S. Kerstein, Eleonore Valencia, Shane Collins, Alessandra M. Ferraro, David M. Harrild, Kimberlee Gauvreau, Ryan Callahan, Mary P. MullenBoston Children’s Hospital and Harvard Medical School. Children’s Hospital of Philadelphia.United States Pediatric CardiologyPediatr Cardiol 2023; DOI: 10.1007/s00246-023-03233-7 AbstractBackground: Interventional therapies for severe pulmonary arterial hypertension (PAH) can provide right ventricular (RV) decompression and preserve cardiac output. Transcatheter

Transcatheter Ductus Arteriosus Stenting for Acute Pediatric Pulmonary Arterial Hypertension is Associated with Improved Right Ventricular Echocardiography Strain Read More »

Practices and Outcomes from a Prospective, Multicenter Registry for Preterm Newborns with Pulmonary Hypertension

Nicolle Fernandez Dyess, Claire Palmer, Roger F. Soll, Reese H. Clark, Steven H. Abman, John P. Kinsella and the Preterm Newborn Pulmonary Hypertension Registry Study Group with Multiple Collaborating InvestigatorsUniversity of Colorado School of Medicine. University of Vermont. Pediatrix Center for Research. Multiple Collaborating Institutions.United States Journal of PediatricsJ Pediatr 2023; DOI: 10.1016/j.jpeds.2023.113614 AbstractObjective: To describe current

Practices and Outcomes from a Prospective, Multicenter Registry for Preterm Newborns with Pulmonary Hypertension Read More »

Variants in FGF10 cause early onset of severe childhood interstitial lung disease: A detailed description of four affected children

Katharina Schutz, Axel Schmidt, Nicolaus Schwerk, Diane Miriam Renz, Benedicte Gerard, Elise Schaefer, Maria Cristina Antal, Sophia Peters, Matthias Griese, Christina K. Rapp, Hartmut Engels, Kristen Cremer, Anke Katharina Bergmann, Gunnar Schmidt, Bernd Auber, Jan C. Kamp, Florian Laenger, Sandra von HardenbergHannover Medical School. School of Medicine, University Hospital Bonn and University of Bonn. German

Variants in FGF10 cause early onset of severe childhood interstitial lung disease: A detailed description of four affected children Read More »

Cardiopulmonary physiological effects of diuretic therapy in preterm infants with chronic pulmonary hypertension

Faith Zhu, Daniel Ibarra Rios, Sebastien Joye, Michelle Baczynski, Danielle Rios, Regan E. Giesinger, Patrick J. McNamara, Amish JainMount Sinai Hospital and University of Toronto. Hospital Infantil de México Federico Gómez. Lausanne University Hospital. University of Iowa.Canada, Mexico, Switzerland and United States Journal of PerinatologyJ Perinatol 2023DOI: 10.1038/s41372-023-01742-0 AbstractObjective: Using targeted neonatal echocardiography (TNE) to examine cardiopulmonary

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Pre-Flight Hypoxemia Challenge Testing in Bronchopulmonary Dysplasia

Jonathan C. Levin, Catherine A. Sheils, Lystra P. HaygenBoston Children’s Hospital and Brigham and Women’s Hospital.United States PediatricsPediatrics 2023; 152DOI: 10.1542/peds.2022-061001 AbstractBackground and objectives: Former premature infants with bronchopulmonary dysplasia (BPD) are at risk for hypoxemia during air travel, but it is unclear until what age. We aimed to determine pass rates for high altitude simulation testing

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Role of left atrial hypertension in pulmonary hypertension associated with bronchopulmonary dysplasia

Rachel T. Sullivan, Megha D. Tandel, Shazia Bhombal, Gregory T. Adamson, Derek B. Boothroyd, Michael Tracy, Amanda Moy, Rachel K. HopperVanderbilt University Medical Center. Stanford University.United States Frontiers in PediatricsFront Pediatr 2022; DOI: 10.3389/fped.2022.1012136 AbstractLeft atrial hypertension (LAH) may contribute to pulmonary hypertension (PH) in premature infants with bronchopulmonary dysplasia (BPD). Primary causes of LAH in

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