Class 3. Pulmonary Hypertension Associated with Lung Disease

Effects of Ponderal Index on Neonatal Mortality and Morbidities in Extremely Premature Infants

Jae Kyoon Hwang, Ha-Na Kang, Ja-Hye Ahn, Hyun Ju Lee, Hyun-Kyung Park, Chang-Ryul KimHanyang University Guri Hospital. Cheongju St. Mary’s Hospital. Hanyang University Seoul Hospital. Republic of Korea Journal of Korean Medical ScienceJ Korean Med Sci 2022; 37: DOI: 10.3346/jkms.2022.37.e198 AbstractBackground: To evaluate how intrauterine stress affects extremely premature infants in terms of intrauterine growth restriction. We […]

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Oral hymecromone decreases hyaluronan in human study participants

Joelle I. Rosser, Nadine Nagy, Riya Goel, Gernot Kaber, Sally Demirdjian, Jamie Saxena, Jennifer B. Bollyky, Adam R. Frymoyer, Ana E. Pacheco-Navarro, Elizabeth B. Burgener, Jayakumar Rajadas, Zhe Wang, Olga Arbach, Colleen E. Dunn, Anissa Kalinowski, Carlos E. Milla, Paul L. BollykyStanford University. UCSF School of Pharmacy. Charité-Universitätsmedizin Berlin, Freie Universität Berlin, Humboldt-Universität Zu Berlin

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Response categorization and outcomes in extremely premature infants born at 22-26 weeks gestation that received inhaled nitric oxide for hypoxic respiratory failure

Timothy J. Boly, John M. Dagle, Jonathan M. Klein, Danielle R. Rios, Patrick J. McNamara, Regan E. GiesingerUniversity of Iowa.United States Journal of PerinatologyJ Perinatol 2023; 43: 324-331DOI: 10.1038/s41372-022-01582-4 AbstractObjective: To evaluate the outcomes of extremely premature infants who received inhaled nitric oxide(iNO) for hypoxic respiratory failure(HRF).Study design: Retrospective analysis of 107 infants born 22-26 weeks gestation who

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Review of the Pathologic Characteristics in Myhre Syndrome: Gain-of-Function Pathogenic Variants in SMAD4 cause a Multisystem Fibroproliferative Response

Lois J. Starr, Mark E. Lindsay, Deborah Perry, Gregory Gheewalla, Paul A. VanderLaan, Adnan Majid, Charlie Strange, George-Claudiu Costea, Adrian Lungu, Angela E. LinUniversity of Nebraska Medical Center. Harvard Medical School and MassGeneral Hospital for Children. Massachusetts General Hospital. Methodist Hospital. Tufts University School of Medicine. Beth Israel Deaconess Medical Center. Medical University of South

Review of the Pathologic Characteristics in Myhre Syndrome: Gain-of-Function Pathogenic Variants in SMAD4 cause a Multisystem Fibroproliferative Response Read More »

MRI evaluation of right heart functions in children with mild cystic fibrosis

Hafize Otcu Temur, Alpay Alkan, Can Yilmaz Yozgat, Erkan Cakir, Hakan Yazan, Fatma Celik Yabul, Dilek Hacer Cesme, Yilmaz YozgatBezmialem Vakif University. Istanbul Medipol University.Turkey Cardiology in the YoungCardiol Youg 2022; 13: DOI: 10.1017/S1047951122003249 AbstractBackground: This study aimed to assess the ventricular anatomy, function of the right ventricle, and the haemodynamic findings of pulmonary artery in children

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Alveolar dead space fraction is not associated with early RV systolic dysfunction in pediatric ARDS

Daniel Chilcote, Laura Mercer-Rosa, Yan Wang, Steven M. Kawut, Robert A. Berg, Nadir Yehya, Adam S. HimebauchPerelman School of Medicine at the University of Pennsylvania and Children’s Hospital of Philadelphia. United States Pediatric PulmonologyPediatr Pulmonol 2023; 58: 559-565DOI: 10.1002/ppul.26237 AbstractPrimary hypothesis: We hypothesized that higher alveolar dead space fraction (AVDSf) at pediatric acute respiratory distress syndrome (PARDS)

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Outpatient prescription of pulmonary vasodilator therapy to preterm children with bronchopulmonary dysplasia

Ida Jeremiasen, Karin Tran-Lundmark, Mikaela Dolk, Estelle NaumburgLund University and Skåne University Hospital. Umeå University.Sweden Acta PaediatricaActa Paediatr 2023; 112: 409-416DOI: 10.1111/apa.16615 Abstract Aim: The use of pulmonary vasodilator therapy in children born preterm is largely unknown. Our aim was to map prescription patterns in children with bronchopulmonary dysplasia in Sweden.Methods: This was a descriptive national registry-based study

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Pharmacokinetics of L-Citrulline in Neonates at Risk of Developing Bronchopulmonary Dysplasia-Associated Pulmonary Hypertension

Candice D. Fike, Charul Avachat, Angela K. Birnbaum, Judy L. Aschner, Catherine M. SherwinUniversity of Utah Health. University of Minnesota. Hackensack Meridian School of Medicine. Wright State University Boonshoft School of Medicine and Dayton Children’s Hospital.United States Paediatric DrugsPaediatr Drug 2023; 25: 87-96DOI: 10.1007/s40272-022-00542-x AbstractBackground: Options to treat pulmonary hypertension (PH) in neonates with bronchopulmonary dysplasia (BPD)

Pharmacokinetics of L-Citrulline in Neonates at Risk of Developing Bronchopulmonary Dysplasia-Associated Pulmonary Hypertension Read More »

The biventricular contribution to chronic pulmonary hypertension of the extremely premature infant

Gabriela de Carvalho Nunes, Punnanee Wutthigate, Jessica Simoneau, Adrian Dancea, Marc Beltempo, Claudia Renaud, Gabriel AltitMcGill University Health Centre and Montreal Children’s Hospital. Siriraj Hospital and Mahidol University. Canada and Thailand Journal of PerinatologyJ Perinatol 2023; 43: 174-180DOI: 10.1038/s41372-022-01497-0 AbstractObjective: Evaluate factors associated with significant pulmonary hypertension [PH] (≥2/3 systemic) and its impact on ventricular function at

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Characterisation of paediatric pulmonary hypertensive vascular disease from the PPHNet Registry

Steven H. Abman, Mary P. Mullen, Lynn A. Sleeper, Eric D. Austin, Erika B. Rosenzweig, John P. Kinsella, D. Dunbar Ivy, Rachel K. Hopper, J. Usha Raj, Jeffrey Fineman, Roberta L. Keller, Angela Bates, Usha S. Krishnan, Catherine M. Avitabile, Alexander Davidson, Marc D. Natter, Kenneth D. MandlPediatric Pulmonary Hypertension NetworkUnited States and Canada European Respiratory JournalEur Respir J 2021; DOI: 10.1183/13993003.03337-2020 ExtractBackground: There are limited data about the range of diseases, natural history, age-appropriate end-points and optimal care for children with pulmonary hypertension (PH), including the need for developing

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