Class 3. Pulmonary Hypertension Associated with Lung Disease

Postnatal management of preterm infants with congenital diaphragmatic hernia

Emma Williams, Stephanie Lau, Nimrah Abbasi, Eveline Lapidus-Krol, Priscilla P. L. Chiu, Brian T. KalishHospital for Sick Children and University of Toronto. Mount Sinai Hospital. Canada Pediatric Surgery InternationalPediatr Surg Int 2025; 41: DOI: 10.1007/s00383-025-05964-5 AbstractIntroduction: Congenital diaphragmatic hernia (CDH) in the preterm population is increasingly common in the current era of fetal endoluminal tracheal occlusion (FETO)

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Scoping review of initiation criteria for inhaled nitric oxide in preterm infants (born <34 weeks) after 7 days of age

Shin Kato, Yohei Minamitani, Miku Hosokawa, Toshinori Nakashima, Sota Iwatani, Katsuya Hirata, Arata Oda, Takushi Hanita, Masafumi Miyata, Fumihiko Namba, Masayuki Ochiai, Atsushi Nakao, Seiji Yoshimoto, Daichi Suzuki, Erika Ota, Hidehiko Nakanishi, on behalf of the Japan Society for Neonatal Health and DevelopmentJapanese Red Cross Aichi Medical Center Nagoya Daini Hospital. Saitama Medical Center and

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A Delicate Balance: Anesthetic Management for Neonatal Congenital Diaphragmatic Hernia Repair

Mohamad A. Omar, Tamer Ghoneim, Hind KhaleelEmirates Health Services.United Arab Emirates CureusCureus 2024; 16:DOI: 10.7759/cureus.75506 AbstractCongenital diaphragmatic hernia (CDH) presents significant challenges in neonatal management, particularly in the context of anesthesia. This case report details the successful anesthetic management of a five-day-old neonate with left-sided CDH requiring thoracoscopic repair. A five-day-old neonate, delivered via emergency cesarean

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Endothelial Cpt1a Inhibits Neonatal Hyperoxia-Induced Pulmonary Vascular Remodeling by Repressing Endothelial-Mesenchymal Transition

Xiaoyun Li, Katy Hegarty, Fanjie Lin, Jason L. Chang, Amro Abdalla, Karthik Dhanabalan, Sergey O. Solomevich, Wenliang Song, Karim Roder, Chenrui Yao, Wenju Lu, Peter Carmeliet, Gaurav Choudhary, Phyllis A. Dennery, and Hongwei YaoBrown University. Providence VA Medical Center. Warren Alpert Medical School of Brown University. Jinan University. First Affiliated Hospital of Guangzhou Medical University.

Endothelial Cpt1a Inhibits Neonatal Hyperoxia-Induced Pulmonary Vascular Remodeling by Repressing Endothelial-Mesenchymal Transition Read More »

Influence of inhaled nitric oxide on bronchopulmonary dysplasia in preterm infants with PPHN or HRF at birth: a propensity score matched study

Xue-rong Huang, Lian Wang, Guo-bao Liang, Sheng-qian Huang, Bao-ying Feng, Lu Zhu, Xu-fang Fan, Mu-lin Yao, Jing Zhang, Meng-jiao Wang, Zhi Zheng, Yao Zhu, Wen-li Duan, Zhan-kui Li, Jian Mao, Li Ma, Fa-lin Xu, Fan Wu, Qiu-fen Wei, Ling Liu, Xin-zhu LinWomen and Children’s Hospital of Xiamen University School of Medicine. Xiamen Key Laboratory of

Influence of inhaled nitric oxide on bronchopulmonary dysplasia in preterm infants with PPHN or HRF at birth: a propensity score matched study Read More »

LPS Increases Artery but Not Airway Contraction in Precision Cut Lung Slices from a Mouse Model of ARDS

Emma Lamanna, Zoe F. Kropf, Raymond Luong, Matthew Narayan, Elizabeth A. Richards, Bailey Cardwell, Simon G. Royce, Claudia A. Nold-Petry, Jane E. BourkeMonash University. RMIT University. Royal Melbourne Institute of Technology. Hudson Institute of Medical Research.Australia American Journal of Respiratory Cell and Molecular BiologyAm J Respir Cell Mol Biol 2024; DOI: 10.1165/rcmb.2024-0249OC AbstractAcute respiratory distress syndrome

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Inhaled Nitric Oxide Treatment of Early Pulmonary Hypertension to Reduce the Risk of Death or Bronchopulmonary Dysplasia in Infants Born Extremely Preterm: A Masked Randomized Controlled Trial

Hussnain Mirza, Jorge Garcia, Matthew Zussman, Rajan Wadhawan, Julie Pepe, William OhAdvent Health for Children.United States Journal of PediatricsJ Pediatr 2024; DOI: 10.1016/j.jpeds.2024.114427 AbstractObjective: To determine whether inhaled nitric oxide (iNO) treatment of early pulmonary hypertension (PH) would decrease the risk of death or bronchopulmonary dysplasia (BPD) among infants born extremely preterm.Study design: This was a single-center, masked,

Inhaled Nitric Oxide Treatment of Early Pulmonary Hypertension to Reduce the Risk of Death or Bronchopulmonary Dysplasia in Infants Born Extremely Preterm: A Masked Randomized Controlled Trial Read More »

Management and Follow-Up of a Cohort of Neonates With Meconium Aspiration Syndrome Before and After the Revision of the 2015 Neonatal Resuscitation Program

Inês Silva Costa, Jose Alarcão, Ana Rodrigues Silva, Raquel HenriquesUnidade Local de Saúde (ULS) de Viseu Dão-Lafões. Unidade Local de Saúde (ULS) de Coimbra.Portugal CureusCureus 2024; 16: DOI: 10.7759/cureus.72894 AbstractIntroduction: Meconium aspiration syndrome (MAS) is a respiratory condition associated with high morbimortality. Standards of care changed over the years addressing its specificities, aiming to decrease poor respiratory

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Pulmonary hypertension in preterm neonates with bronchopulmonary dysplasia: a meta-analysis

Dwayne Mascarenhas, Marwa Al-Balushi, Aida Al-Sabahi, Dany E. Weisz, Amish Jain, Bonny JasaniHospital for Sick Children and University of Toronto. Sunnybrook Health Sciences Centre. Mount Sinai Hospital. Canada Archive of Disease in Children Fetal and Neonatal EditionArch Dis Child Fetal Neonatal Ed 2024; DOI: 10.1136/archdischild-2024-327547 AbstractContext: Knowledge gaps exist on the incidence and risk factors for developing

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Treprostinil Use in the NICU

Diana LeeUniversity of Pennsylvania School of Nursing.United States Advances in Neonatal CareAdv Neonat Care 2024; 24: 554-560DOI: 10.1097/ANC.0000000000001218 AbstractBackground: Treprostinil is a prostacyclin analogue that is frequently used in the pediatric and adult population to treat pulmonary hypertension; however, it is not often a drug of choice for patients in the neonatal intensive care unit (NICU).Purpose: To evaluate

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