Class 2. Pulmonary Hypertension Associated with Valvular Disease of the Left Side of the Heart

Case Report: A case of severe pulmonary hypertension combined with FBN1 mutation associated geleophysic dysplasia

Ze-yang Chen, Yuan Cao, Jie Yang, Xue-hua He, Li-ping Liu, Yong-hua YuanQingdao University School of Medicine. Hunan Provincial People’s Hospital and First Affiliated Hospital of Hunan Normal University.China Frontiers in PediatricFront Pediatr 2025; DOI: 10.3389/fped.2025.1642390 AbstractBackground: FBN1 gene mutation-associated geleophysic dysplasia (GD) leads to the formation of complex and refractory pulmonary hypertension (PH) through a multifactorial combination […]

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Percutaneous Balloon Mitral Valvuloplasty in Children and Adolescents With Juvenile Rheumatic Mitral Stenosis: Single Centre Experience

Abhay Pota, Tarun Parmar, Priyanka Agarwal, Bhavik Champaneri, Amit Mishra, Trushar Gajjar, Jigar Surti, Shilpa Deodhar, Amit Kungwani, Gajendra DubeyUN Mehta Institute of Cardiology and Research Centre. India CureusCureus 2025; 17: DOI: 10.7759/cureus.84707 AbstractBackground Rheumatic mitral stenosis (MS) in India is known to affect at a younger age, worsen rapidly, and have severe valvar and subvalvar

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Unusual Pulmonary Manifestation in a Child With Congenital Mitral Stenosis: A Case Report

Ola Alhalabi, Ahmed Abushahin, Atqah AbdulwahabSidra Medicine.Qatar CureusCureus 2025; 17: DOI: 10.7759/cureus.80575 AbstractCongenital mitral valve stenosis (MVS) in children is usually isolated. However, it is, in rare cases, associated with secondary pulmonary hemosiderosis. It is hypothesized that secondary pulmonary hemosiderosis results from chronic pulmonary venous congestion and repeated microvascular hemorrhage due to elevated left atrial pressure.

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Pulmonary hypertension in infancy: a reversible cause

Cassandra Campbell, Kawaljeet Singh, Mark Weems, Panjit PhilipUniversity of Tennessee Health Science Center.United States British Medical Journals Case ReportsBMJ Case Rep 2025; 18:DOI: 10.1136/bcr-2024-263731 AbstractA term, healthy infant presented with respiratory distress and severe pulmonary hypertension (PH). With an unclear aetiology and the intent to decrease right ventricular afterload, pulmonary vasodilators were initiated. Follow-up imaging revealed

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Clinical Management and Transplant Considerations in Pediatric Pulmonary Hypertension Due to Left Heart Disease: A Scientific Statement From the American Heart Association

Rachel K. Hopper, Georg Hansmann, Seth A. Hollander, Anne I. Dipchand, Oscar van der Have, Colleen Iler, Cynthia Herrington, Erika B. Rosenzweig, Juan C. Alejos, Karin Tran-Lundmark, on behalf of the American Heart Association Council on Cardiopulmonary, Critical Care, Perioperative & Resuscitation; Council on Clinical Cardiology; and Council on Cardiovascular Stroke NursingLucille Packard Children’s Hospital

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Left-Sided Atrioventricular Valve Regurgitation After the Repair of Complete Atrioventricular Septal Defect

Takaya Hoashi, Akinori Hirano, Ryusuke Hosoda, Haruhiro Nagase, Yuji Fuchigami, Yukino Iijima, Takaaki SuzukiSaitama Medical University International Medical Center.Japan Pediatric CardiologyPediatr Cardiol 2024; DOI: 10.1007/s00246-024-03707-2 AbstractThis study aimed to investigate left-sided atrioventricular valve outcome after the repair of complete atrioventricular septal defect from single-institutional retrospective chart review. From 1998 to 2022, 55 patients with complete atrioventricular

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Mitral Valve Intervention, Pulmonary Hypertension, and Survival in 219 Shone’s Syndrome Patients

Dominique L. Tucker, Sohini Gupta, Amol Pande, Rashed Mahboubi, Miza Salim Hammoud, Munir Ahmad, Hani Najm, Tara Karamlou, Shone’s Syndrome Working GroupCleveland Clinic, Cleveland and Case Western Reserve University School of Medicine. United States Annals of Thoracic SurgeryAnn Thorac Surg 2024; DOI: 10.1016/j.athoracsur.2023.10.023 AbstractBackground: Relationships between pulmonary hypertension (PHTN), mitral valve intervention (MVI), and death among patients

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Accidental finding of ALCAPA in a child with severe mitral regurgitation: A case study

Budi Rahmat, Radityo Prakoso, Rafles Ph Simbolon, Albert T. Lopolisa, Muhammad Rayhan, Eva M. MarwaliNational Cardiovascular Center Harapan Kita and Universitas Indonesia. Indonesia Asian Cardiovascular Thoracic AnnalsAsian Cardiovasc Thorac Ann 2024; DOI: 10.1177/02184923241295550 AbstractCase report: A six-year-old child who had undergone cardiac surgery five years ago presented to us with severe mitral valve regurgitation. During her current

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Metabolic gene therapy in a canine with pulmonary hypertension secondary to degenerative mitral valve disease

Michael G. Katz, Dan G. Ohad, Philip Putter, Nataly Shtraizent, Ehud Shahar, Smadar Tal, Efrat EliyahuIcahn School of Medicine at Mount Sinai. Veterinary Teaching Hospital of the Koret School of Veterinary Medicine and Hebrew University of Jerusalem. Spot On Veterinary Hospital. Senex. Frezent Biological Solutions. Tel-Hai College. Migal-Galilee Research Institute. United States and Israel Frontiers in Veterinary MedicineFront Vet Med 2024; 11: DOI: 10.3389/fvets.2024.1415030 AbstractMyxomatous

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Clinical presentation and surgical outcomes in patients with Shone’s complex: a systematic review

H. Shafeeq Ahmed, Purva Reddy Jayaram, Deeksha GuptaBangalore Medical College and Research Institute.India General Thoracic and Cardiovascular SurgeryGen Thorac Cardiovasc Surg 2024; DOI: 10.1007/s11748-024-02067-1 AbstractObjective: Shone’s complex comprises of a combination of congenital cardiac anomalies causing obstructions in the left ventricle’s inflow and outflow tracts. This systematic review aims to evaluate the clinical features and surgical outcomes

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