Class 2. Pulmonary Hypertension Associated with Left Ventricular Systolic or Diastolic Dysfunction

Use of SGLT2 (Sodium-Glucose Cotransporter 2) Inhibitors in Pulmonary Hypertension

Benoit Aguado, Grégoire Ruffenach, Thomas Lacoste-Palasset, Agnes Görlach, Marianne Riou, Mathieu Gourmelon, Fabrice Bauer, Marc Humbert, Valerie Schini-Kerth, Jean-Luc Vachiéry, David Montani, Fabrice AntignyUniversité Paris-Saclay and French National Institute for Health and Medical Research. Hôpital Bicêtre and Hôpital Marie Lannelongue. Technical University Munich and German Centre for Cardiovascular Research. Nouvel Hôpital Civil and University Hospital […]

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Volume Loading May Compromise Left Ventricular Filling in Patients with a Borderline Hypoplastic Left Ventricle

Machi Yamashita, Hirofumi Saiki, Kanchi Saito, Akira Sato, Seiko Kuwata, Satoshi Nakano, Hideaki Senzaki, Junichi KoizumiIwate Medical University. Nihon Institute of Medical Science.Japan International Heart JournalInt Heart J 2025; 66: 1019-1024DOI: 10.1536/ihj.25-216 AbstractGiven the high prevalence of end-organ damage in the long term after the Fontan procedure, patients presenting with borderline hypoplastic left ventricle (LV) are

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Cause of death in children with heart disease: a cohort study

Neil Derridj, Daphné Madec, Olivier Raisky, Sophie Malekzadeh-Milani, Diala Khraiche, Antoine Legendre, Lucile Houyel, Zahra Belhadjer, Franck Iserin, Mathilde Méot, Marilyne Levy, Bertrand Stos, Daniela Laux, Victor Waldmann, Vanessa Lopez, Ayman Haydar, Segolene Bernheim, Régis Gaudin, Fanny Bajolle, Damien Bonnet, Members of M3C Necker Collaborative GroupHôpital Universitaire Necker-Enfants Malades. Paris Cité University. France Archives of

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Right ventricular dysfunctions in type 1 diabetic mice: A longitudinal study

Jian-Jian Yu, Jian-Ge Han, Yi Tan, Jian-Xiang Xu, Amanda LeBlanc, Bradley B. Keller, Jiapeng Huang, Lu CaiUniversity of Louisville School of Medicine. Tianjin University Chest Hospital. Cincinnati Children’s Heart Institute and University of Cincinnati. United States and China World Journal of DiabetesWorld J Diabetes 2025; 13: DOI: 10.4239/wjd.v16.i10.109526 AbstractBackground: Diabetes has become a widespread metabolic disease affecting

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Mitochondrial cardiomyopathies: navigating through different clinical and management pictures between adult and paediatric forms

Rachele Adorisio, Nicoletta Cantarutti, Barbara Siri, Elisa Bellettini, Gessica Ingrasciotta, Erica Mencarelli, Francesca Graziani, Rosa Lillo, Sara Di Marzio, Corrado Di Mambro, Fabrizio Drago, Antonio Amodeo, Diego MartinelliBambino Gesù Children’s Hospital. University of Turin. Fondazione Policlinico Universitario A. Gemelli.Italy Frontiers in Cardiovascular MedicineFront Cardiovasc Med 2025; 12: DOI: 10.3389/fcvm.2025.1621096 AbstractMitochondrial diseases (MD) represent a group of

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Clinical characteristics and mortality risk factors in pediatric hypertrophic, restrictive, and rapidly progressive hypertrophic cardiomyopathy: a retrospective cohort study with follow-up

Asad Nawaz, Zixian Sheng, Muhammad Junaid Akram, Jianjin Li, Lingjuan Liu, Yuxing Yuan, Jie TianNational Clinical Research Center for Child Health and Disorders and Children’s Hospital of Chongqing Medical University.China Frontiers in Cardiovascular MedicineFront Cardiovasc Med 2025; 15: DOI: 10.3389/fcvm.2025.1541651 AbstractBackground: Pediatric cardiomyopathies are rare but life-threatening conditions with high mortality. Limited data exists on their clinical

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Temporal changes in prevalence and severity of pulmonary hypertension, and relationship to outcomes in coarctation of aorta

Ahmed Younis, Yogesh N. V. Reddy, William R. Miranda, Ahmed T. Abdelhalim, Barry A. Borlaug, Heidi M. Connolly, Alexander C. EgbeMayo Clinic.United States International Journal of Cardiology Heart and VasculatureInt J Cardiol Heart Vasc 2025; 57: DOI: 10.1016/j.ijcha.2025.101626 AbstractBackground: Pulmonary hypertension (PH) affects 20% of adults with coarctation of aorta (COA). What is not known is whether

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Clinical Management and Transplant Considerations in Pediatric Pulmonary Hypertension Due to Left Heart Disease: A Scientific Statement From the American Heart Association

Rachel K. Hopper, Georg Hansmann, Seth A. Hollander, Anne I. Dipchand, Oscar van der Have, Colleen Iler, Cynthia Herrington, Erika B. Rosenzweig, Juan C. Alejos, Karin Tran-Lundmark, on behalf of the American Heart Association Council on Cardiopulmonary, Critical Care, Perioperative & Resuscitation; Council on Clinical Cardiology; and Council on Cardiovascular Stroke NursingLucille Packard Children’s Hospital

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Clinical Implications of Pretest Probability of HFpEF on Outcomes in Precapillary Pulmonary Hypertension

Yogesh N. V. Reddy, Robert P. Frantz, Paul M. Hassoun, Anna R. Hemnes, Evelyn Horn, Jane A. Leopold, Franz Rischard, Erika B. Rosenzweig, Nicholas S. Hill, Serpil C. Erzurum, Gerald J. Beck, J. Emmanuel Finet, Christine L. Jellis, StephenC. Mathai, W. H. Wilson Tang, Barry A BorlaugMayo Clinic. Johns Hopkins University. Vanderbilt University Medical Center. Weill

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Bullous Lung Disease in Turner Syndrome: An Underrecognized Comorbidity?

Stevin Lu, Lois J. Starr, Rachel A. Taylor, Anji T. YetmanCreighton Medical School. University of Nebraska Medical Center.United States American Journal of Medical Genetics Part AAm J Med Genet A 2024; DOI: 10.1002/ajmg.a.63908 AbstractCongenital pulmonary anomalies in Turner syndrome (TS) are rarely reported. Herein, we describe a female with TS who presented with emphysema in infancy

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