Class 2. Pulmonary Hypertension Associated with Left Ventricular Systolic or Diastolic Dysfunction

Pediatric Heart Transplantation in the Context of Severe Pulmonary Hypertension Secondary to Restrictive Cardiomyopathy-Case Report

Szymon Pawlak, Joanna Sliwka, Joanna Kwiatkowska, Arkadiusz Wierzyk, Agnieszka Kuczaj, Piotr Przybylowski, Tomasz HrapkowiczMedical University of Silesia. Medical University of Gdańsk. Poland Transplantation ProceedingsTransplant Proc 2024;DOI: 10.1016/j.transproceed.2024.03.019 AbstractThe aim of this study is to analyze the feasibility of performing an isolated heart transplant in patients with severe pulmonary hypertension as a result of restrictive cardiomyopathy. The […]

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Congenital Diaphragmatic Hernia Patients with Left Heart Hypoplasia and Left Ventricular Dysfunction Have Highest Odds of Mortality

Maria V. Fraga, Holly L. Hedrick, Natalie E. Rintoul, Yan Wang, Devon Ash, Sabrina J. Flohr, Leny Mathews, Tom Reynolds, Jenny L. Engelman, Catherine M. AvitabileThe Children’s Hospital of Philadelphia and Perelman School of Medicine at the University of Pennsylvania.United States Journal of PediatricsJ Pediatr 2024; DOI: 10.1016/j.jpeds.2024.114061 AbstractObjectives: To describe the scope of left ventricular (LV)

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Atrial Septal Defect, Pulmonary Arterial Hypertension, and Diastolic Left Heart Failure: When 3 Players Come into the Game

Tobias Rutz, John-David Aubert, Maurice Beghetti, Eric Eeckhout, Olivier Muller, Judith Bouchardy, Patrick YerlyLausanne University Hospital and University of Lausanne. Universitaire Romand de Cardiologie et Chirurgie Cardiaque Pédiatrique. Switzerland Circulation Heart FailureCirc Heart Fail 2024;DOI: 10.1161/CIRCHEARTFAILURE.123.010545 AbstractAbstract Not Available CategoryClass I. Pulmonary Hypertension Associated with Congenital Cardiovascular DiseaseClass II. Pulmonary Hypertension Associated with Left Ventricular Systolic

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Stent Implantation Across the Atrial Flow Regulator Device

Enrico Piccinelli, Fausto Frazzetto, Mara Pilati, Gianfranco ButeraBambino Gesù Hospital and Research Institute. Politecnico di Torino. Università del Piemonte Orientale. Italy Pediatric CardiologyPediatr Cardiol 2024;DOI: 10.1007/s00246-024-03405-z AbstractThe Atrial Flow Regulator (AFR) is a self-expandable double-disc device with a central fenestration, intended to maintain a calibrated communication across the interatrial septum. We reported for the first time

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Reassessing the role of milrinone in the treatment of heart failure and pulmonary hypertension in neonates and children: a systematic review and meta-analysis

Felipe Yu Matsushita, Vera Lúcia Jornada Krebs, Carolina Vieira de Campos, Paula Vieira de Vincenzi Gaiolla, Werther Brunow de CarvalhoUniversity of São Paulo. Hospital Samaritano. Brazil European Journal of PediatricsEur J Pediatr 2023; DOI: 10.1007/s00431-023-05342-0 AbstractTo evaluate milrinone’s impact on pediatric cardiac function, focusing on its specific role as an inotrope and lusitrope, while considering its

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Pulmonary hemodynamics before and after pediatric heart transplantation

Philipp Biedermann, Vanessa Sitte-Koch, Martin Schweigger, Anke Meinold, Daniel Quandt, Oliver Kretschmar, Christian Balmer, Walter KnirschUniversity Children’s Hospital Zurich. Switzerland Clinical TransplantationClin Transplant 2023; DOI: 10.1111/ctr.15162 AbstractBackground: Pulmonary hypertension (PH) may limit the outcome of pediatric heart transplantation (pHTx). We evaluated pulmonary hemodynamics in children undergoing pHTx.Methods: Cross-sectional, single-center, observational study analyzing pulmonary hemodynamics in children undergoing pHTx.Results: Twenty-three

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Elastin stabilization prevents impaired biomechanics in human pulmonary arteries and pulmonary hypertension in rats with left heart disease

Mariya M. Kucherenko, Pengchao Sang, Juquan Yao, Tara Gransar, Saphala Dhital, Jana Grune, Szandor Simmons, Laura Michalick, Dag Wulsten, Mario Thiele, Orr Shomroni, Felix Hennig, Ruhi Yeter, Natalia Solowjowa, Gabriela Salinas, Georg N. Duda, Volkmar Falk, Naren R. Vyavahare, Wolfgang M. Kuebler, Christoph KnosallaDeutsches Herzzentrum der Charité. Charité-Universitätsmedizin Berlin. Freie Universität Berlin and Humboldt-Universität zu

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Role of left atrial hypertension in pulmonary hypertension associated with bronchopulmonary dysplasia

Rachel T. Sullivan, Megha D. Tandel, Shazia Bhombal, Gregory T. Adamson, Derek B. Boothroyd, Michael Tracy, Amanda Moy, Rachel K. HopperVanderbilt University Medical Center. Stanford University.United States Frontiers in PediatricsFront Pediatr 2022; DOI: 10.3389/fped.2022.1012136 AbstractLeft atrial hypertension (LAH) may contribute to pulmonary hypertension (PH) in premature infants with bronchopulmonary dysplasia (BPD). Primary causes of LAH in

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Repolarization Dispersion Is Associated With Diastolic Electromechanical Discoordination in Children With Pulmonary Arterial Hypertension

Michal Schäfer, Benjamin S. Frank, D. Dunbar Ivy, Max B. Mitchell, Kathryn K. Collins, Pei-Ni Jone, Johannes C. von AlvenslebenUniversity of Colorado and Children’s Hospital Colorado.United States Journal of the American Heart AssociationJ Am Heart Assoc 2022; 11: DOI: 10.1161/JAHA.121.024787 AbstractBackground: Electromechanical dyssynchrony is a well described comorbidity in pulmonary arterial hypertension (PAH). ECG-derived measurements reflective

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International practice heterogeneity in pre-transplant management of pulmonary hypertension related to pediatric left heart disease

Rachel K. Hopper, Oscar van der Have, Seth A. Hollander, Anne I. Dipchand, Valeria Perez de Sa, Jeffery A. Feinstein, Karin Tran-LundmarkStanford University and Lucille Packard Children’s Hospital. Lund University. Skane University Hospital. University of Toronto and the Hospital for Sick ChildrenUnited States, Sweden and Canada Pediatric TransplantationPediatr Transplant 2023; DOI: 10.1111/petr.14461 AbstractBackground: Elevated pulmonary vascular resistance

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