Class 1. Pulmonary Hypertension Associated with Inflammation

LPS Increases Artery but Not Airway Contraction in Precision Cut Lung Slices from a Mouse Model of ARDS

Emma Lamanna, Zoe F. Kropf, Raymond Luong, Matthew Narayan, Elizabeth A. Richards, Bailey Cardwell, Simon G. Royce, Claudia A. Nold-Petry, Jane E. BourkeMonash University. RMIT University. Royal Melbourne Institute of Technology. Hudson Institute of Medical Research.Australia American Journal of Respiratory Cell and Molecular BiologyAm J Respir Cell Mol Biol 2024; DOI: 10.1165/rcmb.2024-0249OC AbstractAcute respiratory distress syndrome […]

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A bovine model of hypoxia-induced pulmonary hypertension reveals a gradient of immune and matrisome response with a complement signature found in circulation

Jason Williams, Franklyn N. Iheagwam, Sean P. Maroney, Lauren R. Schmitt, R. Dale Brown, Greta M. Krafsur, Maria G. Frid, Maxwell C. McCabe, Aneta Gandjeva, Kurt J. Williams, James P. Luyendyk, . Anthony J. Saviola, Rubin M. Tuder, Kurt Stenmark, Kirk C. HansenUniversity of Colorado Denver and University of Colorado Anschutz Medical Campus. Michigan State

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Immunoregulatory Macrophages Modify Local Pulmonary Immunity and Ameliorate Hypoxic Pulmonary Hypertension

Angelez Fernandez-Gonzalez, Amit Mukhia, Janhavi Nadkarni, Gareth R. Willis, Monica Reis, Kristjan Zhumka, Sally Vitali, Xianlan Liu, Alexandra Galls, S. Alex Mitsialis, Stella KourembanasBoston Children’s Hospital and Harvard Medical School.United States Arteriosclerosis Thrombosis and Vascular BiologyArterioscler Thromb Vasc Biol 2024; DOI: 10.1161/ATVBAHA.124.321264 AbstractBackground: Macrophages play a significant role in the onset and progression of vascular disease in

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The role of immune cells in the pathogenesis of connective tissue diseases-associated pulmonary arterial hypertension

Zhe Li, Juan Ma, Xuejing Wang, Liquan Zhu, Yu Gan, Baoquan DaiWeifang Maternal and Child Health Hospital. Shandong Second Medical University.China Frontiers in ImmunologyFront Immunol 2024; 15: DOI: 10.3389/fimmu.2024.1464762 AbstractConnective tissue diseases-related pulmonary arterial hypertension (CTD-PAH) is a disease characterized by an elevated pulmonary artery pressure that arises as a complication of connective tissue diseases. The

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Lung EC-SOD Overexpression Prevents Hypoxia-Induced Platelet Activation and Lung Platelet Accumulation

Daniel Colon Hidalgo, Mariah Jordan, Janelle N. Posey, Samuel D. Burciaga, Thi-Tina N. Nguyen, Christina Sul, Caitlin V. Lewis 2, Cassidy Delaney, Eva S. NozikUniversity of Colorado Anschutz Medical Campus. United States AntioxidantsAntioxidants 2024; 13: DOI: 10.3390/antiox13080975 AbstractPulmonary hypertension (PH) is a progressive disease marked by pulmonary vascular remodeling and right ventricular failure. Inflammation and oxidative

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Multisystem Inflammatory Syndrome in Neonates Associated with COVID-19 in Neonatal ICU of a Tertiary Care Hospital

Asma Shabbir, Humaira Khurshid, Imran Mahmood KhanFazaia Medical College, Pakistan Air Force Hospital.Pakistan Journal of the College of Physicians and Surgeons PakistanJ Coll Physicians Surg Pak 2024; 34: 727-731 DOI: 10.29271/jcpsp.2024.06.727 AbstractObjective: Neonatal multisystem inflammatory syndrome (MIS-N) is a unique disease of neonates described in several case reports from all over the world with a myriad of

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Interstitial macrophage phenotypes in Schistosoma-induced pulmonary hypertension

Rahul Kumar, Sushil Kumar, Claudia Mickael, Dara Fonseca Balladares, Kevin Nolan, Michael H. Lee, Linda Sanders, Julia Nilsson, Ari B. Molofsky, Rubin M. Tuder, Kurt R. Stenmark, Brian B. GrahamUniversity of California, San Francisco and Zuckerberg San Francisco General Hospital. University of Colorado Anschutz Medical Campus. United States Frontiers in ImmunologyFront Immunol 2024; DOI: 10.3389/fimmu.2024.1372957 AbstractBackground: Schistosomiasis

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NLRP3 Inflammasome Triggers Inflammation of Obstructive Sleep Apnea

Xiaoting Yangzhong, Shu Hua, Yiqiong Wen, Xiaoqing Bi, Min Li, Yuanyuan Zheng, Shibo SunFirst Affiliated Hospital, Kunming Medical University.China Current Molecular MedicineCurr Mol Med 2024; DOI: 10.2174/0115665240294605240426123650 AbstractObstructive sleep apnea [OSA] is widespread in the population and affects as many as one billion people worldwide. OSA is associated with dysfunction of the brain system that controls

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Fatal pulmonary arterial hypertension (PAH): A rare association of anti-MDA-5 positive juvenile dermatomyositis

R. Shreyas, Anagha Patteri, M. B. Hayagrivas, Tanya Singla, Shivaprasad Pannasamudra Mohankumar, Saurabh Kumar Gupta, Manisha Jana, Narendra Kumar Bagri, A. V. RamananAll India Institute of Medical Sciences. Bristol Royal Hospital for Children.India and United Kingdom International Journal of Rheumatic DiseasesInt J Rheum Dis 2024; 27: DOI: 10.1111/1756-185X.15180 AbstractAbstract Not Available CategoryClass I. Pulmonary Hypertension Associated

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Single cell transcriptomic analyses reveal diverse and dynamic changes of distinct populations of lung interstitial macrophages in hypoxia-induced pulmonary hypertension

Sushil Kumar, Claudia Mickael, Rahul Kumar, Ram Raj Prasad, Nzali V. Campbell, Hui Zhang, Min Li, B. Alexandre McKeon, Thaddeus E. Allen, Brian B. Graham, Yen-Rei A. Yu, Kurt R. StenmarkUniversity of Colorado School of Medicine. University of California San Francisco. Zuckerberg San Francisco General Hospital.United States Frontiers in ImmunologyFront Immunol 2024; 15: DOI: 10.3389/fimmu.2024.1372959 AbstractIntroduction: Hypoxia

Single cell transcriptomic analyses reveal diverse and dynamic changes of distinct populations of lung interstitial macrophages in hypoxia-induced pulmonary hypertension Read More »

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