Adult Pulmonary Vascular Disease

Severe Pulmonary Arterial Hypertension in Pregnancy: Multidisciplinary Management and Avoidance of Oxytocin

Kyung-Jin Ahn, Wook-Jin Chung, Albert Youngwoo Jang, Chang Hu Choi, Kyung Cheon Lee, Suk Young KimGachon University and Gachon University Gil Medical Center.Republic of Korea Journal of the American College of Cardiology Case ReportsJACC Case Rep 2026; DOI: 10.1016/j.jaccas.2026.109896 AbstractBackground: Pregnancy in patients with pulmonary arterial hypertension (PAH) carries substantial maternal and fetal risk, necessitating meticulous hemodynamic […]

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Iron Homeostasis at High Altitude in Patients With Pulmonary Hypertension

Aurelia E. Reiser, Markus Thiersch, Max Gassmann, Simon R. Schneider, Laura Mayer, Stéphanie Saxer, Michael Furian, Richard Sparla, Esther I. Schwarz, Mona Lichtblau, Martina U. Muckenthaler, Silvia UlrichUniversity of Zürich and University Hospital of Zurich. Eastern Switzerland University of Applied Sciences. University of Heidelberg. Switzerland and Germany Pulmonary CirculationPulm Circ 2026; 16: DOI: 10.1002/pul2.70352 AbstractIron deficiency

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Repair of Sinus Venosus Atrial Septal Defect in 2 Patients With Severe Pulmonary Arterial Hypertension

Ryo Sakuma, Gareth Morgan, Elizabeth Yeung, Benjamin S. Frank, Charles Simpkin, Dunbar IvyUniversity of Colorado School of Medicine.United States Pulmonary CirculationPulm Circ 2026; 16: DOI: 10.1002/pul2.70285 AbstractPretreatment with targeted pulmonary arterial hypertension (PAH) therapy in adults with unrepaired atrial septal defects (ASDs) has been increasingly reported as a means to improve pulmonary hemodynamics and expand candidacy

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Safety and Efficacy of a Novel Atrial Flow Regulator in Patients With Severe Pulmonary Arterial Hypertension: The AFR-Prophet Study

Jozef Bartunek, Emiliano Fiori, Grzegorz Kopec, Teoman Kilic, Joseph Pattathu, Nikolaus A. HaasAZORG, Sapienza University. University Medical College and John Paul II Hospital in Krakow. Kocaeli University. Ludwig-Maximilians-University Munich.Belgium, Italy, Poland, Turkey and Germany Journal of the Society of Cardiovascular Angiography and InterventionsJ Soc Cardiovasc Angiogr Interv 2026; DOI: 10.1016/j.jscai.2026.104390 AbstractBackground: Pulmonary arterial hypertension (PAH) is a

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Refining the Definition for “Low Risk” in Pulmonary Arterial Hypertension: Time to Reduce Morbidity and Mortality

Charles Fauvel, Priscilla Correa Jaque, Yongqi Liu, Sang Wan Lee, Sandeep Sahay, Nelson A. Villasmil Hernandez, Jason Weatherald, James White, Allen Everett, Megan Griffith, Thomas M. Cascino, Adam Perer, Katelyn Morrison, Michael Lewis, Yuri Matusov, Shili Lin, Raymond L. BenzaRouen University Hospital and French National Institute for Health and Medical Research. Eastern Virginia Medical School,

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The Role of the Cellular Communication Network Protein Family in Pulmonary Arterial Hypertension

Carly E. Byrd, Jennifer E. Schramm, Jun Yang, Allan E. Barnes, Megan Griffiths, William C. Nichols, David D. Ivy, Eric D. Austin, Allen D. EverettJohns Hopkins University. University of Texas Southwestern. Cincinnati Children’s Hospital Medical Center and University of Cincinnati College of Medicine. Children’s Hospital Colorado. Vanderbilt University Medical Center. United States Pulmonary CirculationPulm Circ

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Lactobacillus Is Associated With Disease in Pulmonary Arterial Hypertension: A Prospective Cohort Study

Arun Jose, Senu Apewokin, Nicholas J. Ollberding, Qing Duan, Jennifer Trannguyen, Sasha Z. Prisco, Thenappan Thenappan, Anna R. Hemnes, Jean M. ElwinUniversity of Cincinnati and Cincinnati Children’s Hospital Medical Center. University of Minnesota. Vanderbilt University.United States Comprehensive PhysiologyComp Physiol 2026; 16: DOI: 10.1002/cph4.70161 AbstractBackground: Gut dysbiosis and gut-derived metabolites have been linked to pulmonary arterial hypertension. However,

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Metabolomics of Right Ventricular Function in Pulmonary Hypertension

Jonathan Chacon-Barahona, Samuel J Chung, Jonah D Garry, Robert Frantz, Franz Rischard, Paul M Hassoun, Stephen C Mathai, Catherine E Simpson, Gerald Beck, Nicholas S Hill, Jane A Leopold, Aaron B Waxman, Erika B Rosenzweig, Barry A Borlaug, Monica Mukherjee, Rebecca Vanderpool, Miriam Jacob, Reena Mehra, Margaret M Park, J Emanuel Finet, Samar Farha, Gabriele Grunig, Deborah Kwon, Suzy Comhair, Serpil Erzurum, John Barnard, Bo Hu, Christine L Jellis, Alexandra Christin Racanelli, Jan Krumsiek, Evan L Brittain, Anna Hemnes, Evelyn Horn; PVDOMICS Study GroupWeill Cornell Medical College. Albert

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Transcatheter closure of anomalous systemic arterial supply to the left lung from the left subclavian artery: Diagnostic and procedural challenges

Anil Kumar Singhi, Manojit Lodha, Santunu De, Arpita Choraria, Sandip Sardar, Ejaz Ahmed Bari, Debadri ChakrabartiManipal Hospital EM Bypass. Vivekananda Institute of Medical Sciences. India Journal of Cardiology CasesJ Cardiol Cases 2025 Aug 5; 32: 207-210DOI: 10.1016/j.jccase.2025.07.007 AbstractA 26-year-old woman with chronic effort intolerance and a continuous murmur underwent evaluation for suspected congenital heart disease. While

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Protocol for an open-label, randomised, controlled trial to evaluate the efficacy and safety of sotatercept add-on therapy compared with pulmonary vasodilator-based standard of care for pulmonary vasodilator-resistant pulmonary arterial hypertension associated with unrepaired congenital shunts (atrial septal defect, ventricular septal defect or patent ductus arteriosus), including Eisenmenger syndrome: the SuMILE trial

Keimei Yoshida, Kazuya Hosokawa, Takahiro Hiraide, Satoshi Akagi, Kentaro Ejiri, Yu Taniguchi, Shiro Adachi, Takumi Inami, Naohiko Nakanishi, Masaharu Kataoka, Taijyu Satoh, Shunsuke Tatebe, Toshiro Shinke, Hideshi Tomita, Yusuke Akazawa, Takashi Higaki, Koshiro Tagawa, Ayako Ishikita, Soshun Asakawa, Kohtaro AbeKyushu University and Kyushu University Hospital. Keio University School of Medicine. Okayama University. Kobe University Hospital.

Protocol for an open-label, randomised, controlled trial to evaluate the efficacy and safety of sotatercept add-on therapy compared with pulmonary vasodilator-based standard of care for pulmonary vasodilator-resistant pulmonary arterial hypertension associated with unrepaired congenital shunts (atrial septal defect, ventricular septal defect or patent ductus arteriosus), including Eisenmenger syndrome: the SuMILE trial Read More »

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