Acquired Patient Factors Associated with Pulmonary Vascular Disease

Insulin-like growth factor binding Protein-4: A novel indicator of pulmonary arterial hypertension severity and survival

Guillermo Torres, Jun Yang, Megan Griffiths, Stephanie Brandal, Rachel Damico, Dhananjay Vaidya, Catherine E. Simpson, Michael W. Pauciulo, William C. Nichols, David D. Ivy, Eric D. Austin, Paul M. Hassoun, Allen D. EverettJohns Hopkins University. University of Texas Southwestern Medical Center. Cincinnati Children’s Hospital Medical Center. Children’s Hospital Colorado. Vanderbilt University Medical Center.United States Pulmonary […]

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The Role of the Interleukin-1 Family in Complications of Prematurity

Elys A. Green, Steven P. Garrick, Briana Peterson, Philip J. Berger, Robert Galinsky, Rod W. Hunt, Steven X. Cho, Jane E. Bourke, Marcel F. Nold, Claudia A. Nold-PetryHudson Institute of Medical Research. Monash University. Monash Children’s Hospital. Australia International Journal of Molecular SciencesInt J Mol Sci 2023; 24: DOI: 10.3390/ijms24032795 AbstractPreterm birth is a major contributor

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Functional and molecular determinants of right ventricular response to severe pulmonary hypertension in a large animal model

R. Dale Brown, Kendall S. Hunter, Min Li, Maria G. Frid, Julie Harral, Greta M. Krafsur, Timothy N. Holt, Jason Williams, Hui Zhang, Suzette R. Riddle, Michael G. Edwards, Sushil Kumar, Cheng-Jun Hu, Brian B. Graham, Lori A. Walker, Franklyn B. Garry, Peter M. Buttrick, Tim Lahm, Vitaly O. Kheyfets, Kirk C. Hansen, Kurt R.

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Multiomics endotyping of preterm infants with bronchopulmonary dysplasia and pulmonary hypertension-A pilot study

Roopa Siddaiah, Christiana Oji‐Mmuo, Vincent P. R. Aluquin, Yuka Imamura Kawasawa, Ann Donnelly, Dustin Rousselle, Nathalie Fuentes, Eric D. Austin, Patricia SilveyraPenn State Health and Children’s Hospital. Indiana University School of Public Health. Vanderbilt University.United States Pulmonary CirculationPulm Circ 2023; 13: DOI: 10.1002/pul2.12232 Abstract Pulmonary hypertension associated with bronchopulmonary dysplasia is a severe complication of preterm

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Lactylation: novel epigenetic regulatory and therapeutic opportunities

Haoqin Fan, Fan Yang, Zhenghui Xiao, Haiyan Luo, Huaiyang Chen, Zhi Chen, Qiming Liu, Yunbin XiaoHengyang Medical School and University of South China. Hunan Children’s Hospital. Second Xiangya Hospital, Central South University. China American Journal of Physiology Endocrinology and MetabolismAm J Physiol Endocrinol Metab 2023; 324: E330-E338DOI: 10.1152/ajpendo.00159.2022 AbstractLactate, which is an end product of glycolysis,

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Growth and differentiation factor 15 (GDF15) levels predict adverse respiratory outcomes in premature neonates

Faeq Almudares, Joseph Hagan, Xinpu Chen, Sridevi Devaraj, Bhagavatula Moorthy, Krithika LingappanBaylor College of Medicine. Children’s Hospital of Philadelphia.United States Pediatric PulmonologyPediatr Pulmonol 2023; 58: 271-278DOI: 10.1002/ppul.26197 AbstractGrowth and differentiation factor 15 (GDF15) is a stress-responsive cytokine, and its expression increases during inflammation, hyperoxia, and senescence. Significantly, GDF15 is secreted by the placenta, and maternal levels

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The long-term efficacy in blood transfusions, hematologic parameter changes, and complications after splenectomy in patients with transfusion-dependent thalassemia

Nichanan Osataphan, Somying Dumnil, Adisak Tantiworawit, Teerachat Punnachet, Nonthakorn Hantrakun, Pokpong Piriyakhuntorn, Thanawat Rattanathammethee, Sasinee Hantrakool, Chatree Chai-Adisaksopha, Ekarat Rattarittamrong, Lalita Norasetthada, Kanda Fanhchaksai, Pimlak CharoenkwanChiang Mai University. Thailand Transfusion and Apheresis ScienceTransfus Apher Sci 2022; DOI: 10.1016/j.transci.2022.103620 AbstractBackground: A splenectomy can reduce transfusion requirements in patients with thalassemia. However, the role of a splenectomy remains controversial

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Metabolic Reprogramming of the Right Ventricle and Pulmonary Arteries in a Flow-Associated Pulmonary Arterial Hypertension Rat Model

Dongli Liu, Suyuan Qin, Danyan Su, Kai Wang, Yanyun Huang, Yuqin Huang, Yusheng PangThe First Affiliated Hospital of Guangxi Medical University. The First Affiliated Hospital of Wenzhou Medical University.China American Chemical Society OmegaACS Omega 2021; 7: 1273-1287DOI: 10.1021/acsomega.1c05895 AbstractPulmonary arterial hypertension (PAH) is a complex devastating disease relevant to remarkable metabolic dysregulation. Although various research studies

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Vitamin D Levels and Cardiopulmonary Status in Infants with Acute Bronchiolitis

Ana Estalella-Mendoza, Ana Castellano-Martinez, Jose Carlos Flores-Gonzalez, Lorena Estepapedregosa, Patricia Rodriguez-Campoy, Moises Rodriguez-GonzalezPuerta del Mar University Hospital. Spain Indian PediatricsIndian Pediatr 2022; 59: 384-387DOI: Not Available AbstractBackground: To assess association of Vitamin D deficiency with cardiac and pulmonary status in infants with acute bronchiolitis.Methods: Infants hospitalized with acute bronchiolitis were enrolled and classified as those with serum

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Postoperative Pulmonary Hemodynamics and Systemic Inflammatory Response in Pediatric Patients Undergoing Surgery for Congenital Heart Defects

Maria Francilene S. Souza, Juliano G. Penha, Nair Y. Maeda, Filomena R. B. G. Galas, Kelly C. O. Abud, Eloisa S. Carvalho, Ana Maria Thomaz, Claudia R. P. Castro, Juliana Pereira, Antonio Augusto LopesUniversity of São Paulo School of Medicine. Brazil Mediators of InflammationMediator Inflamm 2022; DOI: 10.1155/2022/3977585 AbstractThere is scarce information about the relationships between

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