Acquired Patient Factors Associated with Pulmonary Vascular Disease

Inpatient outcomes among children with Down syndrome: a Kids’ Inpatient Database study

Po-Yang Tsou, Yu-Hsun Wang, Ignacio E. TapiaBoston Children’s Hospital and Harvard Medical School. Tufts Medical Center. University of Miami Health System.United States BioMedical Central PediatricsBMC Pediatr 2025; 25: DOI: 10.1186/s12887-025-05899-9 AbstractBackground: Children with Down Syndrome (DS) are more likely to have multi-system comorbidities leading to more frequent hospitalizations than the general population. We aim to evaluate whether […]

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Reassessment of the Current Iron Deficiency Definition in Pulmonary Hypertension

Aurelia E. Reiser, Markus Thiersch, Max Gassmann, Martina U. Muckenthaler, Thomas Geiser, Mona Lichtblau, Silvia UlrichUniversity of Zürich. University of Heidelberg. University of Berne.Switzerland and Germany Pulmonary CirculationPulm Circ 2025; 15: DOI: 10.1002/pul2.70142 AbstractIron deficiency (ID) is prevalent in pulmonary hypertension(PH), but there is no consensus on ID definition and its possible correlation to prognostic markers.

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Outcomes of extremely preterm infants with bronchopulmonary dysplasia: a retrospective cohort study

Ashraf Gad, Rowan Mesilhy, Thomas Maveli, FatimaAli, Noora Jasim, MalazAdam, Tasneim Abdalla, Mohamed Madani, Mohammad Ayman Alkhateeb, Mohammad A. A. BayoumiHamad Medical Corporation. Qatar University. Sidra Medicine. Qatar Scientific ReportsSci Rep 2025; 15: DOI: 10.1038/s41598-025-12066-8 AbstractTo investigate the respiratory and related health outcomes at 18 months for extremely preterm (EP) infants diagnosed with bronchopulmonary dysplasia (BPD).

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Distinctive hemodynamic phenotype in Fontan-type circulation patients with distal esophageal varices

Luis Téllez, Luis, María Toledano, María Álvarez, Elvira Garrido-Lestache, Elena Garrido, Antonio Guerrero, Jesús Donate, Lorenzo Canova, María Torres, Cristian Perna, María Jesús del Cerro, Agustín AlbillosHospital Universitario Ramón y Cajal, IRYCIS, CIBERehd, Universidad de Alcalá. Spain HepatologyHepatology 2025;  DOI: 10.1097/HEP.0000000000001472 AbstractBackground aims: Esophageal varices (EV) are common in adults with Fontan-type circulation and may arise via

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Utility of patient-reported outcomes for pulmonary symptoms and sleep disturbance and impairment in children with systemic juvenile idiopathic arthritis

Kim Nguyen, Shima Yasin, Ndate Fall, Alexei A. Grom, Hermine I. Brunner, Christopher Towe, Grant S. SchulertTriHealth Hospital System. University of Cincinnati College of Medicine and Cincinnati Children’s Hospital Medical Center.United States Pediatric Rheumatology Online JournalPediatr Rheumatol Online J 2025; 23: DOI: 10.1186/s12969-025-01126-y AbstractBackground: Patient-reported outcomes (PROs) are critical assessment tools for clinical practice, observational studies, and

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Persistent Pulmonary Hypertension of the Newborn in Very Low Birth Weight Infants: Risk Factors and Clinical Outcomes from a Matched Case-Control Study

Anucha Thatrimontrichai, Pattima Pakhathirathien, Manapat Praditaukrit, Gunlawadee Maneenil, Supaporn Dissaneevate, Ploypailin Jantarawongpisal, Jenjira SaechanPrince of Songkla University.Thailand Journal of Clinical MedicineJ Clin Med 2025; 14: DOI: 10.3390/jcm14134759 AbstractBackground/Objectives: To identify the risk factors and clinical outcomes of persistent pulmonary hypertension of the newborn (PPHN) in very low birth weight (VLBW) infants in a resource-limited setting. Methods: We

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Allergy and atopic phenotype are associated with earlier gestation and severity of respiratory symptoms in bronchopulmonary dysplasia

Brianna C. Aoyama, Joseph M. Collaco, Amit Agarwal, Gangaram Akangire, Eric D. Austin, Manvi Bansal, Anita Bhandari, A. Ioana Critea, Lystra P. Hayden, Jonathan C. Levin, Winston M. Manimtim, Audrey N. Miller, Paul E. Moore, Antonia P. Popova, Lawrence M. Rhein, Catherine A. Sheils, Steven H. Abman, Christopher D. Baker, Sara K. Dawson, Mehtap Haktanir

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Incidence and clinical predictors of hyper-direct bilirubinemia in preterm infants without underlying disease

Takuya Akimoto, Nobuhiko Nagano, Yuki Sato, Hidetoshi Go, Koichiro Hara, Takayuki Imaizumi, Ryoji Aoki, Midori Hijikata, Aya Okahashi, Ichiro MoriokaNihon University School of Medicine. Japan Pediatrics InternationalPediatr Int 2025; DOI: 10.1111/ped.70026 AbstractBackgrounds: This study aimed to identify the incidence and clinical predictors of hyper-direct bilirubinemia (hyper-DB) in preterm infants without underlying diseases.Methods: We enrolled neonates born at <34

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The molecular mechanisms of IUGR programmed adulthood cardiovascular disease

Ting Wu, Wen Zhang, Yangong Wang, Hong Luo, Yifei LiWest China Second University Hospital and Sichuan University. Fudan University. China Frontiers in Cell and Developmental BiologyFront Cell Dev Biol 2025; 13: DOI: 10.3389/fcell.2025.1589038 AbstractIntrauterine growth restriction (IUGR) is secondary to several maternal and fetal adverse conditions. Recently, there is a convincing association between the onset of

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Scurvy, all the faces you can see: our experience and review of the literature

Fabio Toscano, Giuseppina Zirilli, Simone Foti Randazzese, Mariagrazia Carlino, Romina Gallizzi, Malgorzata Wasniewska, Mariella ValenziseUniversity of Messina. Magna Graecia University of Catanzaro.Italy Italian Journal of PediatricsItal J Pediatr 2025; 51: DOI: 10.1186/s13052-025-02014-7 AbstractBackground: In the recent past an incremental incidence of scurvy has been reported in the pediatric population, especially in children with neuropsychiatric disorders and a

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