Acquired Patient Factors Associated with Pulmonary Vascular Disease

Allergy and atopic phenotype are associated with earlier gestation and severity of respiratory symptoms in bronchopulmonary dysplasia

Brianna C. Aoyama, Joseph M. Collaco, Amit Agarwal, Gangaram Akangire, Eric D. Austin, Manvi Bansal, Anita Bhandari, A. Ioana Critea, Lystra P. Hayden, Jonathan C. Levin, Winston M. Manimtim, Audrey N. Miller, Paul E. Moore, Antonia P. Popova, Lawrence M. Rhein, Catherine A. Sheils, Steven H. Abman, Christopher D. Baker, Sara K. Dawson, Mehtap Haktanir […]

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Incidence and clinical predictors of hyper-direct bilirubinemia in preterm infants without underlying disease

Takuya Akimoto, Nobuhiko Nagano, Yuki Sato, Hidetoshi Go, Koichiro Hara, Takayuki Imaizumi, Ryoji Aoki, Midori Hijikata, Aya Okahashi, Ichiro MoriokaNihon University School of Medicine. Japan Pediatrics InternationalPediatr Int 2025; DOI: 10.1111/ped.70026 AbstractBackgrounds: This study aimed to identify the incidence and clinical predictors of hyper-direct bilirubinemia (hyper-DB) in preterm infants without underlying diseases.Methods: We enrolled neonates born at <34

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The molecular mechanisms of IUGR programmed adulthood cardiovascular disease

Ting Wu, Wen Zhang, Yangong Wang, Hong Luo, Yifei LiWest China Second University Hospital and Sichuan University. Fudan University. China Frontiers in Cell and Developmental BiologyFront Cell Dev Biol 2025; 13: DOI: 10.3389/fcell.2025.1589038 AbstractIntrauterine growth restriction (IUGR) is secondary to several maternal and fetal adverse conditions. Recently, there is a convincing association between the onset of

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Scurvy, all the faces you can see: our experience and review of the literature

Fabio Toscano, Giuseppina Zirilli, Simone Foti Randazzese, Mariagrazia Carlino, Romina Gallizzi, Malgorzata Wasniewska, Mariella ValenziseUniversity of Messina. Magna Graecia University of Catanzaro.Italy Italian Journal of PediatricsItal J Pediatr 2025; 51: DOI: 10.1186/s13052-025-02014-7 AbstractBackground: In the recent past an incremental incidence of scurvy has been reported in the pediatric population, especially in children with neuropsychiatric disorders and a

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BMPR-II, caspase-3, HIF-1α, and VE-cadherin profile in Down syndrome children with and without congenital heart disease and pulmonary hypertension

Sri L. Widjaja, Masayu L. Anniazi, Bagus Artiko, Annang G. Moelyo, Mylco T. AhmadwirawanUniversitas Sebelas Maret. Indonesia Narra JNarra J 2025; 5: DOI: 10.52225/narra.v5i1.1244 AbstractSeveral cellular markers have been identified as effective in detecting vascular remodeling recently. The reduced activity of bone morphogenetic protein receptor type-II (BMPR-II), commonly observed in Down syndrome, results in insufficient production

BMPR-II, caspase-3, HIF-1α, and VE-cadherin profile in Down syndrome children with and without congenital heart disease and pulmonary hypertension Read More »

Vasculopathy among children and adolescents with sickle cell disease: the crosstalk with annexin A1, vitamin D, and myocardial iron overload

Mohsen Saleh ElAlfy, Eman Abdel Rahman Ismail, Sara Mostafa Makkeyah, Ahmed Samir, Dina Husseiny Salama, Nanis Mohammed Salah Eldin, Dina Mohamed Fathy ElMaghraby, Nada Ayman Gad, Marwa Fath Ahmed Ali, Fatma Soliman El-Sayed EbeidAin Shams University. National Centre for Radiation Research and Technology, Egyptian Atomic Energy Authority. Minia UniversityEgypt Expert Review of HematologyExpert Rev Hematol

Vasculopathy among children and adolescents with sickle cell disease: the crosstalk with annexin A1, vitamin D, and myocardial iron overload Read More »

Pediatric Pulmonary Hypertension is Associated With Increased Circulating Levels of BMP 7 and CHIP

Edward C. Kirkpatrick, Stephanie Handler, Melodee Liegl, Amy Y. Pan, G. Ganesh Konduri, Todd M. Gudausky, Adeleye J. AfolayanChildren’s Wisconsin and Medical College of Wisconsin.United States Pulmonary CirculationPulm Circ 2024; 15: DOI: 10.1002/pul2.70068 AbstractPulmonary arterial endothelial and smooth muscle cell homeostasis is regulated through the bone morphogenetic protein (BMP) and transforming growth factor beta (TGF-β) receptor

Pediatric Pulmonary Hypertension is Associated With Increased Circulating Levels of BMP 7 and CHIP Read More »

Characteristics and sex differences in bronchopulmonary dysplasia-related pulmonary hypertension

Dansha Zhou, Ting Wang, Yuqin Chen, Yulin Zheng, Yingzhen Zhou, Mingxiang Zhang, Aofeng Liu, Biao Hu, Shuang Fu, Ruixian Wu, Wei Chen, Xiaoli Jiang, Zehui Ye, Yuan Shi, Zhou Fu, Jian WangFirst Affiliated Hospital of Guangzhou Medical University and Guangzhou Medical University. Children’s Hospital of Chongqing Medical University. China BioMedical Central Pulmonary MedicineBMC Pulm Med

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Pulmonary artery systolic pressure associated with inflammatory factors among pediatric congenital heart disease with pulmonary arterial hypertension after cardiopulmonary bypass

WenJuan Li, Wenyuan Shang, Jihong HuangXinhua Hospital, Affiliated to Shanghai Jiao Tong University School of Medicine.China Jornal de PediatriaJ Pediatr 2025; DOI: 10.1016/j.jped.2025.01.006 AbstractObjective: This study aimed to evaluate the perioperative inflammatory cytokines in pediatric patients with pulmonary arterial hypertension secondary to congenital heart disease and also sought to investigate the correlation between preoperative echocardiographic pulmonary artery

Pulmonary artery systolic pressure associated with inflammatory factors among pediatric congenital heart disease with pulmonary arterial hypertension after cardiopulmonary bypass Read More »

Placental growth factor modulates endothelial NO production and exacerbates experimental hepatopulmonary syndrome

Fabien Robert, Feriel Benchenouf, My Ngoc Ha, Alessandra Cuomo, Mina Ottaviani, Maxime Surbier, Raphaël Thuillet, Corinne Normand, Florent Dumont, Céline Verstuyft, Frederic Fiore, Frederic Guinut, Marc Humbert, Audrey Coilly, Emmanuel Gonzales, Olivier Sitbon, Ly Tu, Christophe Guignabert, Laurent SavaleUniversité Paris-Saclay. Federico II University. Aix Marseille Université. Hôpital Bicêtre. Hôpital Paul Brousse. France and Italy JHEP

Placental growth factor modulates endothelial NO production and exacerbates experimental hepatopulmonary syndrome Read More »

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