Acquired Patient Factors Associated with Pulmonary Vascular Disease

Reduced gastrointestinal iron uptake in pulmonary arterial hypertension: a prospective cross-sectional study

Luisa Repsold, Satenik Harutyunova, Ekkehard Grünig, Nicola Benjamin, Panagiota Xanthouli, Benjamin Egenlauf, Andreea Florea, Memoona Shaukat, Richard Sparla, Christina Mertens, Martina U. Muckenthaler, Christina A. EichstaedtHeidelberg University Hospital. German Center for Lung Research.Germany Respiratory ResearchRespir Res 2026; DOI: 10.1186/s12931-026-03592-8 AbstractBackground: Iron deficiency (ID) is common in patients with pulmonary arterial hypertension (PAH) and is associated with […]

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Association Between Hemodynamic Parameters and Gut Microbiota in Fontan Circulation: A Cross-Sectional Study

Saviga Sethasathien, Chanon Kunasol, Suchaya Silvilairat, Rekwan Sittiwangkul, Pannipa Suwannasom, Nipon Chattipakorn, Krit Leemasawat, Siriporn C. ChattipakornChiang Mai University. Thailand Journal of the American Heart AssociationJ Am Heart Assoc 2026; DOI: 10.1161/JAHA.125.045962 AbstractBackground: The Fontan operation results in chronic hemodynamic alterations, including central venous hypertension, which may contribute to gut dysbiosis. This study aimed to compare gut

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Liver herniation in congenital diaphragmatic hernia is associated with delayed resolution of pulmonary hypertension

Uthaya Kumaran Kanagaraj, Mimi T.Y. Kuan, Michael Castaldo, Erik Skarsgard, Joseph Y. TingUniversity of British Columbia. University of Alberta.Canada Pediatrics and NeonatologyPediatr Neonatol 2026; DOI: 10.1016/j.pedneo.2025.11.011 AbstractBackground: Severe and persistent pulmonary hypertension (PH) predicts mortality and short-term pulmonary morbidity in infants with congenital diaphragmatic hernia (CDH). Intrathoracic liver herniation (liver-up) is a predictor of survival and increased

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Prevalence and severity of persistent pulmonary hypertension of the newborns among asphyxiated neonates admitted in Enugu State University Teaching Hospital

Ani Okechukwu, Odutola Odetunde, Ekwochi Uchenna, Josephat M ChinawaEnugu State University College of Medicine. University of Nigeria Teaching Hospital Ituku/Ozalla and University of Nigeria ItukuNigeria British Medical Journal Paediatrics OpenBMJ Paediatr Open 2026; 10: DOI: 10.1136/bmjpo-2025-004351 AbstractBackground: Persistent pulmonary hypertension of newborns (PPHN) is an acute neonatal disorder with a high mortality rate despite several advances in

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Fibrotic liver injury in biliary atresia: long-term implications

Maria Hukkinen, Mikko P PakarinenNew Children’s Hospital, University of Helsinki and Helsinki University Hospital.Finland World Journal of Pediatric SurgeryWorld J Pediatr Surg 2025; 8: DOI: 10.1136/wjps-2025-001098 AbstractNormalization of serum bilirubin after Kasai portoenterostomy (KPE) is a prerequisite for long-term native liver (NL) survival. Following a successful KPE, fibrotic liver injury progresses variably, although a significant proportion

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Gut Microbiota in Pulmonary Arterial Hypertension: Murine Models and Human Microbial Signatures, Pathogenic Mechanisms, and Emerging Therapeutic Avenues

Yudan Qiu, Xiaojiang Lyu, Dashuang Zhang, Hong Xu, Xu He, Jiao Chen, Hanmin Liu, Yang Liu, Liang XieWest China Second University Hospital and Sichuan University. School of Life Sciences of Fudan University and West China Institute of Women and Children’s Health. Affiliated Hospital of North Sichuan Medical College. Affiliated Hospital of Southwest Medical University. Xizang

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Inflammatory processes may predispose children to high-altitude pulmonary edema

Anthony G. Durmowicz, Edward Nordeweir, Richard Nicholas, John T. ReevesUniversity of Colorado Health Sciences Center.United States Journal of PediatricsJ Pediatr 1997; 130: 838-480DOI: 10.1016/s0022-3476(97)80033-9 AbstractWe investigated retrospectively whether the preexistence of inflammation-producing illnesses such as viral respiratory tract infections contributed to the development of high-attitude pulmonary edema in children. We found that the large majority of

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Viral respiratory infection increases susceptibility of young rats to hypoxia-induced pulmonary edema

Todd C. Carpenter, John T. Reeves, Anthony G. DurmowitzUniversity of Colorado Health Sciences Center.United States Journal of Applied PhysiologyJ Appl Physiol 1998; 84: 1048-1054 DOI: 10.1152/jappl.1998.84.3.1048 AbstractRecent clinical observations of a high incidence of preexisting respiratory infections in pediatric cases of high-altitude pulmonary edema prompted us to ask whether such infections would increase the susceptibility to hypoxia-induced

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Lymphocytes and immunoglobulins in peripheral blood and lymphatic fluid of neonates with chylothorax

Domenico Umberto De Rose, Francesca Landolfo, Flaminia Pugnaloni, Fatima Zahra Gassabi, Ludovica Martini, Alessandra Santisi, Claudia Columbo, Paola Giliberti, Fabia Gazzotti, Ottavia Porzio, Claudia Capponi, Carlo Federico Perno, Maria Paola Ronchetti, Andrea Conforti, Guglielmo Salvatori, Irma Capolupo, Andrea Dotta“Bambino Gesù” Children’s Hospital IRCCS. “Tor Vergata” University of Rome. Italy Frontiers in ImmunologyFront Pediatr 2025; 16:

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Association Between Steady-State Lactate Dehydrogenase Levels and Sickle Cell Complications: A Systematic Review

Sagad O.O. Mohamed, Amged Mohammed, Fatima S.K. Salih, Hozifa A.M. Elgadal, Ayman A.A. Elsamany, Mohamed S.K. Salih, Huda M.A. Mustafa, Israa Elawad, Mona G.A. Ahmedkaroum, Safaa G.A. Saeed, Rowa E.A. Ibrahim, Esraa A. Mohamedien, Aya A.H. Babiker, Esraa T. Suliman, Eman O.E. MohamedUniversity of Khartoum. Médecins Sans Frontières. University of Bahri. Ibri Regional Hospital. Harlem

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