Gabriel Altit, Anie Lapointe, Florian, Kipfmueller, Neil Patel
Montreal Children’s Hospital and McGill University Health Centre. Centre Hospitalier Universitaire Sainte-Justine. Children’s Hospital University of Bonn. Royal Hospital for Children.
Canada, Germany and United Kingdom
Seminars in Pediatric Surgery
Semin Pediatr Surg 2024; 33:
DOI: 10.1016/j.sempedsurg.2024.151438
Abstract
Cardiac function is known to play critical role in the pathophysiological progression and ultimate clinical outcome of patients with congenital diaphragmatic hernia (CDH). While often anatomically normal, the fetal and neonatal heart in CDH can suffer from both right and left ventricular dysfunction. Here we explore the abnormal fetal heart, early postnatal right and left ventricular dysfunction, the interplay between cardiac dysfunction and pulmonary hypertension, evaluation and echocardiographic assessment of the heart, and therapeutic strategies for managing and supporting the pathophysiologic heart and CDH. Further, we take a common clinical scenario and provide clinically relevant guidance for the diagnosis and management of this complex process.
Category
Class III. Pulmonary Hypertension Associated with Lung Hypoplasia
Right Heart Dysfunction Associated with Pulmonary Vascular Disease
Diagnostic Testing for Pulmonary Vascular Disease. Non-invasive Testing
Review Articles Concerning Pulmonary Vascular Disease
Age Focus: Pediatric Pulmonary Vascular Disease
Fresh or Filed Publication: Fresh (PHresh). Less than 1-2 years since publication
Article Access
Free PDF File or Full Text Article Available Through PubMed or DOI: No