Atrial fibrillation-induced severe left ventricular dysfunction postmitral valve replacement in an adolescent with rheumatic mitral regurgitation

Raghuraj Chawla, Yash Shrivastava, Anish Gupta, Bhanu Duggal
All India Institute of Medical Science Rishikesh.
India

British Medical Journal Case Reports
BMJ Case Rep 2026; 19:
DOI: 10.1136/bcr-2025-267313

Abstract
An adolescent boy with a history of chronic rheumatic heart disease (RHD) and severe mitral regurgitation presented with progressive exertional dyspnoea and palpitations. Echocardiography revealed preserved left ventricular function preoperatively, and the patient underwent mechanical mitral valve replacement (MVR). Postoperative management included anticoagulation and RHD prophylaxis. 4 months later, he developed acute heart failure (New York Heart Association class IV) secondary to atrial fibrillation (AF) with rapid ventricular rate despite a normally functioning prosthetic mitral valve. Echocardiography showed significant left atrium and ventricle dilatation, with severe left ventricle dysfunction (left ventricle ejection fraction (LVEF) ~14%), severe tricuspid regurgitation and pulmonary hypertension. The patient was stabilised with rate control, diuretics, inotropes, digoxin, anticoagulation and intravenous amiodarone. Notably, the LVEF improved to 30%, and he was discharged in stable condition.This case highlights the challenges in managing a paediatric patient with AF and severe LV dysfunction following MVR.

Category
Class II. Pulmonary Hypertension Associated with Left Ventricular Systolic or Diastolic Dysfunction

Age Focus: Pediatric Pulmonary Vascular Disease

Fresh or Filed Publication: Fresh (PHresh). Less than 1-2 years since publication

Article Access
Free PDF File or Full Text Article Available Through PubMed or DOI: No

Scroll to Top