Kyohei Isshiki, Karuko Shima, Fumito Yamazaki, Toshiki Takenouchi, Hiroyuki Shimada
Keio University School of Medicine
Japan
Journal od Pediatric Hematology Oncology
J Pediatr Hematol Oncol 2020; 42(7):e677-e679
DOI: 10.1097/MPH.0000000000001566
Abstract
Pulmonary veno-occlusive disease (PVOD) is an uncommon form of pulmonary hypertension that is usually difficult to diagnose and is refractory to conservative treatment. PVOD can occur in connection with high-dose chemotherapy or hematopoietic stem cell transplantation, similar to hepatic veno-occlusive disease (HVOD). Here, we present a case of neuroblastoma with PVOD following HVOD after high-dose chemotherapy that was resolved with conservative treatment. Respiratory symptoms or edema after HVOD may suggest PVOD, and prompt diagnosis on high-resolution computed tomography will result in a favorable prognosis.
Category
Class I. Pulmonary Veno-occlusive Disease and Pulmonary Capillary Hemangiomatosis
Age Focus: Pediatric Pulmonary Vascular Disease
Fresh or Filed Publication: Filed (PHiled). Greater than 1-2 years since publication
Article Access
Free PDF File or Full Text Article Available Through PubMed or DOI: Yes