Navaneetha Sasikumar, Pranoti Toshniwal. Usha Mandikal Kondakarna Sastry, Shweta Bakhru, Jayaranganath Mahimarangaiah, Nageshwara Rao Koneti, Raman Krishna Kumar
Amrita Institute of Medical Sciences. Sri Jayadeva Institute of Cardiovascular Sciences and Research. Rainbow Children’s Hospital.
India
Pediatric Cardiology
Pediatr Cardiol 2025;
DOI: 10.1007/s00246-025-03849-x
Abstract
KONAR-MF™ device is a novel, cone-shaped, medium profile, self-expanding, double-disk, nitinol occlusive device designed for the ventricular septal defect (VSD). Due to its unique design and easy deployment from either side and multiple occlusion layers, it has also been used to occlude defects other than VSD. A retrospective review was done from 2019 to 2024 from three institutions. All patients where the KONAR-MF™ device was used other than for VSD closure were included in this study. Standard post-procedure follow-up was at 1, 6, and 12 months for all patients. 79 off-label implantations of the KONAR-MF™ device were done for conditions that included 59 shunt lesions (patent ductus arteriosus -34, coronary arteriovenous fistula -12, pulmonary arteriovenous fistula -2, systemic arteriovenous fistula -3, aortopulmonary window -3, aortopulmonary collateral -5, Fontan fenestration closures -7, Fontan antegrade pulmonary valve closures -2, Abernethy malformations -3, decompressing vein -2, and paravalvular leak -2, others 4. The median fluoroscopy time was 10 min (IQR 6-18). The median duration of hospital stay was 2 days (IQR 1-4 days). There were no significant complications. Complete occlusion at the end of the procedure was documented in 72 (91.13%) patients. At a median follow-up of 18 months (IQR 12-28 months) in all except one patient who had mild residual flow with no device-/(procedure) related complications. The unique structure and compact profile of KONAR-MF™ enable a wide range of uses in catheter-based management of various CHDs with the potential to simplify the inventory of the catheterization laboratory.
Category
Class I. Pulmonary Hypertension Associated with Congenital Cardiovascular Disease
Pulmonary Arteriovenous Malformations
Abnormal Systemic to Pulmonary Arterial Collaterals or Connections
Surgical and Catheter-mediated Interventions for Pulmonary Vascular Disease
Age Focus: Pediatric Pulmonary Vascular Disease or Adult Pulmonary Vascular Disease
Fresh or Filed Publication: Fresh (PHresh). Less than 1-2 years since publication
Article Access
Free PDF File or Full Text Article Available Through PubMed or DOI: No