John T. Wren, Neil Patel, Matthew T. Harting, Patrick J. McNamara
University of Iowa Hospitals and Clinics. Royal Hospital for Children. McGovern Medical School at the University of Texas Health Science Center and Children’s Memorial Hermann Hospital.
United States and United Kingdom
Journal of Perinatology
J Perinatol 2025;
DOI: 10.1038/s41372-025-02265-6
Abstract
Despite a near universal approach focused on physiologic stabilization prior to surgical repair of congenital diaphragmatic hernia (CDH), a condition with significant morbidity and mortality, there remains a lack of consensus, or even guidance, on the appropriate timing for diaphragmatic reconstruction. Hemodynamic-directed care has increasingly been incorporated into the post-natal, peri-operative care of CDH, including assessments of pulmonary hypertension and ventricular dysfunction. Herein, we discuss the integration of targeted neonatal echocardiography and hemodynamic-based assessments to guide precision-directed care and inform selection of the optimal surgical repair window in this complex, heterogeneous patient population.
Category
Class III. Pulmonary Hypertension Associated with Lung Hypoplasia
Diagnostic Testing for Pulmonary Vascular Disease. Non-invasive Testing
Review Articles Concerning Pulmonary Vascular Disease
Age Focus: Pediatric Pulmonary Vascular Disease
Fresh or Filed Publication: Fresh (PHresh). Less than 1-2 years since publication
Article Access
Free PDF File or Full Text Article Available Through PubMed or DOI: No