Technical problems in lung allotransplantation. Causes of pulmonary venous outflow obstruction

Gary H. Stevens, Decio M. Rangel, Yozo Yakeishi, Eric W. Fonkalsrud
UCLA School of Medicine.
United States

Archives of Surgery
Arch Surg 1969; 99: 506-512
DOI: 10.1001/archsurg.1969.01340160086020

Abstract
Experience in this laboratory with approximately 100 canine and primate lung allotransplantation operations over the past 18 months has made clear the fact that technical problems are the cause of a large number of graft failures.
In our series of 80 canine lung allotransplants which have been examined postmortem, more than 50% of failures appeared to be due to complete or partial obstruction to venous outflow from the graft. At least three distinct types of venous obstruction were encountered. The type of obstruction appears to be related to the duration of the posttransplant period, and may be characterized as acute, intermediate, and chronic venous outflow obstruction.

Category
Segmental Pulmonary Venous Disease. Without a Focus on Pulmonary Hypertension
Lung Transplantation for Pulmonary Vascular Disease
Animal Models of Pulmonary Vascular Disease and Therapy

Age Focus: Pediatric Pulmonary Vascular Disease or Adult Pulmonary Vascular Disease

Fresh or Filed Publication: Filed (PHiled). Greater than 1-2 years since publication

Article Access
Free PDF File or Full Text Article Available Through PubMed or DOI: No

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