Unilateral Pulmonary Arteriosclerosis Unusual Fibrous Connective Tissue Growth Associated; Review of Literature and Discussion of Possible Physiological Mechanisms Involved in These Changes

Scott R. Inkley, George R. Abbott
Western Reserve University and University Hospitals of Cleveland.
United States

Journal of the American Medical Association Internal Medicine
JAMA Int Med 1961; 108: 903-915
https://doi:10.1001/archinte.1961.03620120087012

Abstract
An extensive fibrous connective tissue proliferation suggestive of retroperitoneal fibrosis or chronic mediastinitis is reported here. Aside from being the most extensive involvement that we can find after reviewing the literature, this lesion produced a most interesting natural experiment in the development of pulmonary arteriosclerosis. This change was unilateral and associated with complete obstruction of the pulmonary vein on the involved side. Although there have been several case reports of pulmonary vein obstruction in association with a similar lesion, none of these has been unilateral and unaccompanied by cor pulmonale.

Category
Class II. Pulmonary Hypertension Associated with Pulmonary Vein Stenosis
Pulmonary Vascular Pathology
Review Articles Concerning Pulmonary Vascular Disease

Age Focus: Adult Pulmonary Vascular Disease

Fresh or Filed Publication: Filed (PHiled). Greater than 1-2 years since publication

Article Access
Free PDF File or Full Text Article Available Through PubMed or DOI: No

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