Lora Grozdeva, Marie-Victoire Senat, Nada Vandewynckele, Virginie Fouquet, Vanina Castaigne, Gwenaelle Le Bouar, Alexandra Benachi, Hanane Bouchghoul
Bicêtre Hospital, Antoine Béclère Hospital, Assistance Publique-Hôpitaux de Paris and University Paris Saclay. Intercommunal Créteil Hospital. CHU de Rennes.
France
Fetal Diagnosis and Therapy
Fetal Diagn Ther 2021; 48: 34-42
DOI: 10.1159/000510823
Abstract
Objective: The objective of this study is to assess the effectiveness and safety of intrafetal vascular laser ablation (VLA) for fetuses with bronchopulmonary sequestration (BPS) with hydrops.
Methods: First, we present 3 cases of fetuses with BPS and hydrops treated by VLA. Second, we aimed to conduct a narrative review to identify all reported cases of fetuses with BPS treated by intrafetal VLA.
Results: The review of the literature identified 41 fetuses treated by VLA for BPS with hydrops. The median gestational age of the VLA was 27+0 weeks’ gestation [25+0-31+0] with an associated procedure at the same time in 43% of the cases (pleuroamniotic shunt, thoracentesis, and amniodrainage). A second procedure was required in 25% of cases for residual flow in the feeding vessel. No stillbirth or neonatal death was reported. The complications reported were a fetal thoracic hematoma complicated by fetal anemia and 4 preterm deliveries with a rate of 9%.
Conclusion: VLA of the feeding vessel can be an effective treatment but is not without complications. In cases demonstrating cardiac output failure, intrafetal VLA should be considered as a treatment for BPS.
Category
Abnormal Systemic to Pulmonary Arterial Collaterals or Connections
Surgical and Catheter-mediated Interventions for Pulmonary Vascular Disease
Age Focus: Pediatric Pulmonary Vascular Disease
Fresh or Filed Publication: Filed (PHiled). Greater than 1-2 years since publication
Article Access
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