Timothy Klouda, Francis Fynn-Thompson, Kathy Jenkins, Michael Farias, Christina M. Ireland, Jennifer Mosey, Wai Wong, Saba Sheikh, Christian Benden, Gary Visner
Boston Children’s Hospital and Harvard Medical School.
United States
Journal of Heart and Lung Transplantation Open
JHLT Open 2026; 14:
DOI: 10.1016/j.jhlto.2026.100650
Abstract
Pulmonary vein stenosis (PVS) is characterized by luminal narrowing from neointimal proliferation, leading to the obstruction of pulmonary venous blood flow. Lung transplantation is considered a definitive treatment for patients with severe and progressive PVS that is unresponsive to treatment. We present a case in which a three-year-old female who received a bilateral lung transplant for PVS was diagnosed with disease recurrence in multiple veins. This case highlights the need to discuss the possibility of PVS returning during pre-transplant counseling and advocates for frequent monitoring in the post-transplant period.
Category
Segmental Pulmonary Venous Disease. Without a Focus on Pulmonary Hypertension
Lung Transplantation for Pulmonary Vascular Disease
Age Focus: Pediatric Pulmonary Vascular Disease
Fresh or Filed Publication: Fresh (PHresh). Less than 1-2 years since publication
Article Access
Free PDF File or Full Text Article Available Through PubMed or DOI: Yes