Anthony G. Durmowicz, Edward Nordeweir, Richard Nicholas, John T. Reeves
University of Colorado Health Sciences Center.
United States
Journal of Pediatrics
J Pediatr 1997; 130: 838-480
DOI: 10.1016/s0022-3476(97)80033-9
Abstract
We investigated retrospectively whether the preexistence of inflammation-producing illnesses such as viral respiratory tract infections contributed to the development of high-attitude pulmonary edema in children. We found that the large majority of native low-attitude children, but not adults, who had this form of edema after traveling to high altitude also had evidence of a preexisting illness. We speculate that the release of inflammatory mediators associated with these illnesses may be tolerated at sea level but may predispose children to increased capillary permeability when superimposed on hypoxia and, possibly, cold and exercise.
Category
High Altitude Pulmonary Edema
Acquired Patient Factors Associated with Pulmonary Vascular Disease
Age Focus: Pediatric Pulmonary Vascular Disease
Fresh or Filed Publication: Filed (PHiled). Greater than 1-2 years since publication
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