Exchange transfusion for hyperleucocytosis in a critical case of pertussis

Nihil Akcay, Demet Tosun, Ilyas Bingöl
University of Health Sciences, Kanuni Sultan Suleyman Training and Research Hospital.
Turkey

Paediatrics and International Child Health
Paediatr Int Child Health 2025;
DOI: 10.1080/20469047.2025.2595836

Abstract
An 8-week-old infant girl with pertussis-induced respiratory distress, complicated by severe leucocytosis, pulmonary hypertension and respiratory failure is reported. She was treated with mechanical ventilation, exchange transfusion and other supportive measures. A single-volume exchange transfusion significantly reduced the elevated white blood cell count and stabilised her condition. This case underscores the potential role of exchange transfusion as a life-saving intervention in critical pertussis cases with severe leucocytosis.

Category
Class I. Pulmonary Hypertension Associated with Infection
Medical Therapy. Efficacy or Lack of Efficacy

Age Focus: Pediatric Pulmonary Vascular Disease

Fresh or Filed Publication: Fresh (PHresh). Less than 1-2 years since publication

Article Access
Free PDF File or Full Text Article Available Through PubMed or DOI: No

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