Infective Endocarditis and Meningitis in a Healthy Newborn Without Underlying Heart Disease, Due to Streptococcus Agalactiae-A Case Report

Dalal S. Idris, Muath M. Al Ghamdi, Maria L. Bello Valls, Mohammed Fararjeh
Ministry of the National Guard – Health Affairs. King Abdullah International Medical Research Center. King Saud bin Abdulaziz University for Health Sciences. Security Forces Hospital.
Saudi Arabia

Journal of the Saudi Heart Association
J Saudi Heart Assoc 2025; 37:
DOI: 10.37616/2212-5043.1453

Abstract
Streptococcus Agalactiae endocarditis is a rare clinical entity in newborns with a normal structured heart. It is generally characterized by acute onset, the presence of large vegetations, rapid valvular destruction and frequent complications, particularly embolization. Mortality is high with medical therapy alone. We are reporting a rare case of infective endocarditis (IE) with mitral valve vegetation in a 9 days old healthy newborn following Streptococcus Agalactiae sepsis, complicated by meningitis and micro-abscesses. Mitral valve (MV) vegetation was removed surgically; the patient received intravenous antibiotics for six weeks. Transthoracic echocardiography after surgery showed severe MV regurgitation and severe pulmonary hypertension which was successfully managed by conservative care with cardiac medications.

Category
Class II. Pulmonary Hypertension Associated with Valvular Disease of the Left Side of the Heart

Age Focus: Pediatric Pulmonary Vascular Disease

Fresh or Filed Publication: Fresh (PHresh). Less than 1-2 years since publication

Article Access
Free PDF File or Full Text Article Available Through PubMed or DOI: Yes

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