Christine L. Farrell, Mariah Jordan, Janelle N. Posey, Kimberly R. Jordan, Aneta Gandjeva, Eva S. Nozik, Kurt R. Stenmark, Rubin M. Tuder, Brian B. Graham, Cassidy A. Delaney
University of Colorado Anschutz Medical Campus and Children’s Hospital Colorado. University of California San Francisco.
United States
Pulmonary Circulation
Pulm Circ 2025; 15:
DOI: 10.1002/pul2.70174
Abstract
Using lung immunohistochemistry and stereology, platelets were found to accumulate and co-localize with leukocytes, particularly monocytes, within the mural and adventitial space of remodeled vessels of patients with pulmonary arterial hypertension. The presumed signaling between these cell types invites further studies into the role of platelet-monocyte aggregates in pulmonary hypertension.
Category
Pulmonary Vascular Pathology
Vascular Cell Biology and Mechanisms of Pulmonary Vascular Disease
Age Focus: Pediatric Pulmonary Vascular Disease or Adult Pulmonary Vascular Disease
Fresh or Filed Publication: Fresh (PHresh). Less than 1-2 years since publication
Article Access
Free PDF File or Full Text Article Available Through PubMed or DOI: Yes