Roberto Tambucci, Xavier Stephenne, Aniss Channaoui, Catherine de Magnée
Cliniques Universitaires Saint-Luc and UCLouvain.
Belgium
World Journal of Hepatology
World J Hepatol 2025; 17:
DOI: 10.4254/wjh.v17.i7.103179
Abstract
Portal hypertension and cirrhosis are associated with severe hemodynamic changes in hepatic and systemic circulation in the adult population. During cirrhosis progression, circulation becomes hyperdynamic, with cardiac, pulmonary and renal consequences. Cirrhotic adults also present with cirrhotic cardiomyopathy, with systolic and diastolic dysfunction and electrophysiological abnormalities. This article provides an update on normal liver hemodynamics, a brief reminder of the liver and systemic hemodynamics in cirrhotic adults, and a description of liver and systemic hemodynamics in cirrhotic children. This review attempts to clarify whether liver and systemic hemodynamics are altered in cirrhotic children like they are in adults. The characterization of these hemodynamic disturbances could contribute to a better understanding of hepatic and systemic physiopathology in pediatric cirrhosis.
Category
Class I. Pulmonary Hypertension Associated with Liver Disease
Pulmonary Arteriovenous Malformations
Review Articles Concerning Pulmonary Vascular Disease
Age Focus: Pediatric Pulmonary Vascular Disease
Fresh or Filed Publication: Fresh (PHresh). Less than 1-2 years since publication
Article Access
Free PDF File or Full Text Article Available Through PubMed or DOI: Yes